Perflubron: Difference between revisions

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Perflubron
Clinical data
ATC code	V08CX01 (WHO) ;
Identifiers
	IUPAC name 1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane;
CAS Number	423-55-2;
PubChem CID	9873;
ChemSpider	9489;
ChEMBL	ChEMBL1200866;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C8BrF17
Molar mass	498.96 g/mol
3D model (JSmol)	Interactive image;
Density	1.93 g/cm3
Melting point	6 °C (42.8 °F)
Boiling point	142 °C (287.6 °F)
	SMILES FC(F)(C(F)(F)C(Br)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F;
	InChI InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26; Key:WTWWXOGTJWMJHI-UHFFFAOYSA-N;

VisualWikitext

Latest revision as of 16:55, 20 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography.It was approved for this use in the United States by the Food and Drug Administration in 1993.

Experimental research

Perflubron has also been tested experimentally for use in liquid breathing in premature infants with respiratory distress.

References

Template:Contrast media

@@ Line 51: / Line 51: @@
 {{CMG}}
 ==Overview==
-'''Perflubron''' ([[International Nonproprietary Name|INN]]/[[United States Adopted Name|USAN]], or '''perfluorooctyl bromide'''; brand name '''Imagent''') is a [[contrast medium]] for [[magnetic resonance imaging]], [[computer tomography]] and [[sonography]].<ref>{{cite pmid|2643258}}</ref> It was approved for this use in the United States by the [[Food and Drug Administration]] in 1993.<ref>[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.DrugDetails FDA Approved Drug Products]</ref>
+'''Perflubron''' ([[International Nonproprietary Name|INN]]/[[United States Adopted Name|USAN]], or '''perfluorooctyl bromide'''; brand name '''Imagent''') is a [[contrast medium]] for [[magnetic resonance imaging]], [[computer tomography]] and [[sonography]].It was approved for this use in the United States by the [[Food and Drug Administration]] in 1993.
 ==Experimental research==
 Perflubron has also been tested experimentally for use in [[liquid breathing]] in premature infants with respiratory distress.
-:''See also [[Liquid breathing#Medical treatment]] for more information on this potential application.''
-[[File:Molecular ball-and-stick model of Perflubron, overlayed with electron-denisty coded VdW model.png|thumb|This molecular model of Perflubron is color-coded by electron density to illustrate the positive polarisation of the large bromine atom by the inductively electron-withdrawing perfluorooctyl chain.]]
+[[File:Molecular ball-and-stick model of Perflubron, overlayed with electron-denisty coded VdW model.png|none|left|300px]]
 ==References==
 {{reflist|2}}

Clinical data

ATC code	V08CX01 (WHO)
Identifiers
IUPAC name 1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
CAS Number	423-55-2
PubChem CID	9873
ChemSpider	9489
ChEMBL	ChEMBL1200866
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₈BrF₁₇
Molar mass	498.96 g/mol
3D model (JSmol)	Interactive image
Density	1.93 g/cm³
Melting point	6 °C (42.8 °F)
Boiling point	142 °C (287.6 °F)
SMILES FC(F)(C(F)(F)C(Br)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 Key:WTWWXOGTJWMJHI-UHFFFAOYSA-N

Perflubron: Difference between revisions

Latest revision as of 16:55, 20 August 2015

Overview

Experimental research

References

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