Chromoblastomycosis medical therapy: Difference between revisions
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{{Chromoblastomycosis}} | {{Chromoblastomycosis}} | ||
==Overview== | |||
==Medical Therapy== | |||
Chromoblastomycosis is very difficult to cure. There are two primary treatments of choice. Itraconazole, an [[antifungal]] [[azole]], is given orally, with or without [[flucytosine]] (5-FC). Alternatively, [[cryosurgery]] with [[liquid nitrogen]] has also been shown to be effective. Other treatment options are the antifungal drug [[terbinafine]], an experimental drug [[posaconazole]], and [[heat therapy]]. [[Antibiotics]] may be used to treat bacterial superinfections. | |||
{{ | ===Antimicrobial regimen=== | ||
*'''Chromoblastomycosis'''<ref>{{cite book | last = Gilbert | first = David | title = The Sanford guide to antimicrobial therapy | publisher = Antimicrobial Therapy | location = Sperryville, Va | year = 2015 | isbn = 978-1930808843 }}</ref> | |||
:*'''1. If lesions small and few''' | |||
::* surgical excision or cryosurgery with liquid nitrogen. | |||
:*'''2. If lesions chronic, extensive, burrowing''' | |||
::*Preferred regimen: [[Itraconazole]] 200-400 mg PO q24h {{or}} 400 mg pulse therapy once daily for 1 week monthly for 6-12 months | |||
==References== | ==References== | ||
Latest revision as of 13:00, 6 August 2015
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Chromoblastomycosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Chromoblastomycosis medical therapy On the Web |
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Risk calculators and risk factors for Chromoblastomycosis medical therapy |
Overview
Medical Therapy
Chromoblastomycosis is very difficult to cure. There are two primary treatments of choice. Itraconazole, an antifungal azole, is given orally, with or without flucytosine (5-FC). Alternatively, cryosurgery with liquid nitrogen has also been shown to be effective. Other treatment options are the antifungal drug terbinafine, an experimental drug posaconazole, and heat therapy. Antibiotics may be used to treat bacterial superinfections.
Antimicrobial regimen
- Chromoblastomycosis[1]
- 1. If lesions small and few
- surgical excision or cryosurgery with liquid nitrogen.
- 2. If lesions chronic, extensive, burrowing
- Preferred regimen: Itraconazole 200-400 mg PO q24h OR 400 mg pulse therapy once daily for 1 week monthly for 6-12 months
References
- ↑ Gilbert, David (2015). The Sanford guide to antimicrobial therapy. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808843.