Property:AnswerAExp
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Insulin, like PDGF, uses the intrinsic tyrosine kinase activity to achieve its hormonal effects. +
Pernicious anemia is an autoimmune disease characterized by the presence of auto-antibodies against gastric parietal cells. It causes vitamin B12 deficiency. It is also associated with HLA-DR5 subtype. +
Renin is the enzyme that converts angiotensinogen to angiotensin I. Renin inhibitors act at this level. +
The step corresponds to the reaction catalyzed by the enzyme phosphlipase A2. It is inhibited by corticosteroids. +
Angiotensinogen is formed by the liver. It is converted to angiotensin I by renin. Renin is synthesized and stored in the juxtraglomerular apparatus of the kidney. +
LTB4 is a neutrophil chemotactic agent. It does not play a major role in reducing platelet aggregation. +
Polyhormone secretion in gastrinoma, such as co-secretion of gastrin and ACTH, is associated with poorer prognosis. +
An example of procedure bias is when subjects of two arms of a study experience a different course during the study or are treated differently. +
The patient did not describe any financial issues with his non-adherence. There is no reason to jumps to conclusions that may sometimes reflect personal judgment. +
Hereditary spherocytosis (HS) is an autosomal dominant genetic disorder characterized by the hemolysis and increased bilirubin that prediposes affected patients to gallbladder stones. Since the disease is autosomal dominant, a positive family history of HS is typical and thus a positive family history of cholecystectomy should raise the suspicion of HS in young patients presenting with jaundice and anemia. +
IgG4 subtype is most commonly observed in idiopathic membranous nephropathy. In contrast, IgG1, 2, and 3 are more commonly observed in secondary forms of membranous nephropathy. The difference between the two may aid in the differentiation between primary (idiopathic) and secondary membranous nephropathy. +
Giant cell tumor presents commonly in early adulthood at the epiphyseal end of long bones. It is a benign tumor with local aggressive features. Xray shows a "double-bubble" sign. On pathology, it is characterized by spindle-shaped cells with multinucleated giant cells, hence its name. +