Property:AnswerEExp
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''G6PD'' gene mutation results in glucose-6-phosphate dehydrogenase (G6PD) deficiency that causes a decrease in glutathione and an increased susceptibility to oxidant stress. Patients present with back pain, dark-colored urine, and severe pallor following exposure to triggers, such as fava beans intake, infections, or drugs. Labs typically demonstrate anemia and hemoglobinuria. Peripheral smear shows RBCs with Heinz bodies and bite cells. +
Receptors for oxytocin, TRH, Histamine-1 (H1), arginine vasopressor receptor-1 (V1), angiotensin II, and gastrin are inositol triphosphate (IP3) receptors. +
Along with the flexor pollicis brevis, both the abductor pollicis brevis and the opponens pollicis are components of the thenar muscles. They are both innervated by the recurrent branch of the median nerve. The abductor pollicis brevis is responsible for thumb abduction, while the opponens pollicis is responsible for thumb opposition. +
The statement is true for first-order reactions. In zero-order reactions, the eliminated amount is constant regardless of plasma concentrations. +
Adrenal insufficiency is an important cause of hypoglycemia, but given the documented elevation in insulin levels, it is low on the list of differentials. +
Although severe invasive disease may cause obstruction and eventually lead to renal failure, given it's common localization in the peripheral zone, progression to renal failure is not a very common. +
Chloramphenicol inhibits elongation by blocking the peptidyl-transferase halting protein synthesis. Tetracyclines do not affect the peptidyl-transferase enzyme. +
The main etiology of anaphylaxis in patients undergoing transfusions is host antibodies against donor IgA molecules, particularly in patients who are IgA-deficient. These patients might have urticaria, but their symptoms are much more severe, and if untreated progress to cardiovascular collapse. +
Finasteride is a selective inhibitor of 5-alpha-reductase used in the treatment of androgenetic alopecia. +
Leuprolide is a GnRH analogue. When dosed continuously, it inhibits the production of FSH and LH, thereby leading to hypogonadism. When dosed in a pulsatile manner, it increases the production of FSH and LH. In turn, FSH and LH stimulate the production of sex hormones. +