Property:AnswerEExp
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Because carbon monoxide (CO) has a 200x higher affinity for hemoglobin than does oxygen, an increase in CO would cause a non-competitive decrease in the oxygen binding capacity of hemoglobin. +
''' Incorrect ''' : Dietary modifications would have very little impact on total body iron stores even if no foods containing iron are consumed. +
''' Incorrect ''' : All her offspring cannot be normal because of the autosomal dominant inheritance pattern. +
''' Incorrect ''' : Even though in this patient PT/INR are subtherpeutic, the PTT is therapeutic and hence properly anti-coagulated. +
''' Incorrect ''' : Type I heparin-induced thrombocytopenia that is typically characterized by a slight fall in platelet count (< 50%) within the first two days after heparin initiation and often returns to normal with continued heparin administration. This patient has type II HIT and hence warfarin and all heparin products need to be discontinued. +
''' Correct ''' : This patient has type I HIT patients and can recover even if heparin is continued to be administered. +
''' Incorrect ''' : This patient has VWF deficiency which has to be corrected with desopressin or VWF supplement before proceeding with any surgery. +
''' Incorrect ''' : Intrinsic factor is used to treat megaloblastic anemia caused by its deficiency. +
''' Incorrect ''' : Even though in this patient PT/INR are subtherpeutic, the PTT is therapeutic and hence properly anti-coagulated. +
Maltose is a disaccharide composed of two molecules of glucose. Maltose can be included in the diet of patients with fructose intolerance. +
OTC deficiency is a genetic disorder that is usually inherited in an X-linked recessive pattern. +
NADPH and NAD+ are cofactors for aldose reductase and sorbitol dehydrogenase, respectively. Both enzymes and their cofactors are involved in sorbitol metabolism. ATP is not a cofactor in either reaction. +
An example of a 100% chance of a child developing cystinuria is when both parents have fully manifest disease (both carry 2 mutant alleles). In that case all offspring would have the disease too. +
Incorrect
There is no difference in the medication needs between saphenous vein grafts and internal mammary artery grafts. +
Orthostatic hypotension is defined as a significant drop in blood pressure upon standing. It is diagnosed if there is fall of at least 20 mmHg of systolic blood pressure, or fall of at least 10 mmHg of diastolic pressure within 2-5 minutes of standing from supine or sitting position. +