Property:AnswerBExp
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''' Incorrect ''' : Folic acid is used to treat megaloblastic anemia caused by its deficiency. +
''' Incorrect ''' : Bone marrow biopsy is done to rule out polycythemia vera and other hematological malignancies after initial evaluation of ruling out secondary causes. +
While OTC deficiency is usually inherited in an X-linked pattern, other urea metabolism disorders are usually inherited in an autosomal recessive pattern. +
While glucose is normally converted to sorbitol by the action of aldose reductase and then to fructose by the action of sorbitol dehydrogenase, some cells lack sorbitol dehydrogenase expression (cells of the retina, Schwann cells, and the kidneys) and are predisposed to osmotic damage when exposed to chronically high concentrations of sorbitol. +
While both NAD+ and NADPH are needed for sorbitol metabolism, X corresponds to NADPH and Y corresponds to NAD+, and the order by which the enzymes and their cofactors function in the sorbitol pathway is important. +
The patient's presentation and findings on urinalysis are consistent with cystine stones, which often develop among patients with cystinuria. Phenylalanine reabsorption is not impaired in cystinuria, and urinary concentration of phenylalanine is not typically elevated. +
Had both the child's father and mother been carriers of the mutant allele, they would not have manifested the disease themselves, and their child would have had a 25% chance of developing cystinuria. +
Incorrect
Stable patients should have their ventricular rate controlled first. Aspirin is used more with alone fibrillation to prevent stroke, but oral anticoagulants are recommended in paroxysmal atrial fibrillation. +
Incorrect
Calcium channel blockers as verapamil and diltiazem have not been shown to prevent recurrence of atrial fibrillation in patients with of paroxysmal atrial fibrillation. +
Incorrect
Diltiazem should be avoided in patients with impaired left ventricular function due to negative inotropic effects. +
Incorrect
Nonsteroidal anti-inflammatory drugs don’t reduce mortality in patients with CHF. +
Incorrect
Medical therapy, such as lidocaine, amiodarone, or procainamide, can be used for sustained ventricular tachycardia that is hemodynamically stable. +
It is a fine maculo-papular rash, that begins as 2-10 cm oval red 'herald patch' classically on the abdomen. 7–14 days after the herald patch, many small (5-10 mm) patches of pink or red, flaky, oval-shaped rash appear on the chest or back. The small oval patches may spread in a characteristic pattern called as 'Christmas tree' appearance. The rash may be mild to intensely itchy. It is a self limited condition which usually resolves in 6-8 weeks. +