Property:AnswerDExp
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''' Incorrect ''' : Membrane GPIb/IX of phagocytosed platelets are processed, and their digested peptides are presented by macrophages to autoreactive HLA-restricted CD4+ T cells in immune thrombocytopenic purpura. It is not related to initiation of heparin. +
''' Incorrect ''' : The type I heparin-induced thrombocytopenia is typically characterized by a slight fall in platelet count that occurs within the first two days after heparin initiation and often returns to normal with continued heparin administration. +
''' Correct ''' : Avoid unnecessary treatment of asymptomatic patients with mild to moderate thrombocytopenia (ie, a platelet count greater than 30,000/microL). +
''' Incorrect ''' : An isolated decrease in plasma volume can elevate the hemoglobin, hematocrit, and RBC count. The state of chronically reduced plasma volume with elevated hemoglobin or hematocrit has been called Gaisbock's disease, spurious polycythemia, stress erythrocytosis, apparent polycythemia, and pseudopolycythemia, although many may be examples of smokers' polycythemia. +
''' Incorrect ''' : A low serum Epo level in the patient with erythrocytosis is relatively specific for the diagnosis of polycythemia vera (PV) and erythrocytosis associated with increased serum Epo is unlikely to represent PV and a working diagnosis of secondary erythrocytosis should be made. +
D corresponds to arginosuccinase, which catalyzes the reaction that produces arginine and fumarate. +
D corresponds to argininosuccinase, which catalyzes the reaction that produces arginine and fumarate from argininosuccinate. +
OTC deficiency is a genetic disorder that is usually inherited in an X-linked recessive pattern. +
NADPH and NAD+ are cofactors for aldose reductase and sorbitol dehydrogenase, respectively. Both enzymes and their cofactors are involved in sorbitol metabolism. ADP is not a cofactor in either reaction. +
Cystinuria is inherited in an autosomal recessive pattern. The couple's child has a 0% chance of developing cystinuria. +
This result can be achieved by dividing the difference in systolic and diastolic aortic pressures and dividing by the cardiac output (3.6L/min) +
Incorrect
There is no difference in the medication needs between saphenous vein grafts and internal mammary artery grafts. +
Incorrect
Ibutilide is class III anti arrhythmic that is used for the acute termination of atrial fibrillation and not for long term use. +
Incorrect
ACE inhibitors and beta-blockers do decrease mortality and morbidity in CHF; however their use in acute decompensated heart failure is suspected as they may induce hypotension and further cardiogenic shock. +
Correct
Beta-adrenergic antagonists (metoprolol, bisoprolol, and carvedilol) have been proven to reduce mortality in patients with CHF. +