Property:AnswerDExp
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Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor that can increase vasodilation in response to nitric oxide, thereby improving pulmonary hypertension. Sildenafil is most commonly used to treat erectile dysfunction. +
The intercostal space contains the intercostal Vein, Artery, and Nerve (VAN) in that order from superior to inferior. +
Hydroxylation refers to the addition of an –OH group to a compound. Hydroxylation is an important step in the synthesis of steroid compounds. Proline hydroxylation is accomplished with Vitamin C as a cofactor in the synthesis of collagen. +
GLUT4 is an insulin-responsive glucose transporter found in adipose tissue and muscle that translocates to the cell membrane upon exercise. +
The temporalis is a large muscle on the lateral edge of the skull responsible for closing the jaw. +
Verapamil is a calcium channel blocker that can be used to treat cardiac arrhythmias. It is not an effective antidote for beta-blocker overdose. +
The mesenteric lymph nodes drain the gut. The superior mesenteric lymph nodes drain all parts of the gut proximal to the sigmoid colon. The inferior mesenteric lymph nodes drain lymph from the sigmoid colon to the rectum (above the pectinate line). +
While the liver is the most common site of metastasis in colon cancer patients, cancer cells are more likely to spread to the lymphatics before metastasis. Furthermore, cancers below the pectinate line are more likely squamous cell carcinomas than colorectal adenocarcinomas. +
The linea alba is the fibrous band that runs down the midline of the abdomen atop the rectus abdominus. +
This is the mechanism of action of valproic acid, an antiepileptic agent. Although valproate may be used for migraine prophylaxis, it is not an abortive therapy. +
Allopurinol is a xanthine oxidase inhibitor that decreases the production of uric acid; it is essential in the treatment of tumor lysis syndrome. Tumor lysis syndrome is associated with the release of large amounts of uric acid from ruptured tumor cells. This uric acid can precipitate in the renal tubules, causing acute kidney injury. +
Actinic keratosis is a premalignant condition that occurs commonly in older individuals on sun-exposed areas. These lesions are characterized by a scaly appearance and should be monitored because they may progress to squamous cell carcinoma. +
''S. Saprophyticus'' is a catalase-positive, coagulase-negative, gram-positive coccus with novobiocin resistance. It is the second most common cause of urinary tract infections among sexually active women, following ''E. coli''. +
Patients with De Quervain’s thyroiditis should be treated with NSAIDs to decrease inflammation and a beta-blocker to manage the symptoms of hyperthyroidism in the acute phase. +
The chest x-ray in this patient clearly demonstrates a large left sided pneumothorax. The patient is young and does not seem to have acquired or hereditary risk factors of deep vein thrombosis. +
''' Correct ''' : Spherocytes , microspherocytes, and elliptocytes are seen in autoimmune hemolytic conditions which is associated with Wilson’s disease. +
''' Incorrect ''' : All offspring of affected mothers are affected (although some may be phenotypically normal) and no offspring of affected fathers are affected in mitochondrial inheritance. +