Property:AnswerDExp
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Irinotecan and topotecan inhibit topoisomerase I and prevent the unwinding and replication of DNA. +
Receptors for vitamin D, thyroid hormones (T3 and T4), cortisol, aldosterone, and sex hormones (estrogen, progesterone, and testosterone) are intracellular steroid receptors. +
C5 and C6 nerve roots (and occasionally C7 nerve root) are damaged in Erb palsy, which is characterized by failure to abduct, laterally rotate, supinate, and flex the arm. +
Interleukin 10 is a major regulator of T<sub>reg</sub>-cell activity, and is usually decreased in patients with asthma. +
The radial nerve is responsible for innervating the extensors of the wrist. The radial nerve is damaged by midshaft humeral fractures, such as the one pictured above. +
The opponens pollicis is responsible for the opposing activity of the thumb. It is innervated by the recurrent branch of the median nerve. It is one of the three muscles of the thenar muscles (along with the abductor pollicis brevis and the flexor pollicis brevis). The flexor digitorum superficialis flexes the middle phalanges at the proximal interphalangeal joints. +
Because a constant amount of phenytoin is eliminated per unit time, plasma concentration levels falls linearly. +
Patients with documented type 1 diabetes mellitus who are on insulin therapy can commonly have episodes of hypoglycemia that often only require dose adjustment of their insulin. However, this patient has never been diagnosed with diabetes mellitus, and should not be on therapy. Diabetes mellitus type 1 as a sole etiology would likely cause hyperglycemia. +
The peripheral zone is the most common zone for prostate cancer to develop, making the digital rectal exam a suitable choice to detect larger prostate tumors. +
Macrolides act on the 50S ribosomal subunit (particularly the 23S rRNA) to inhibit protein synthesis. They act by preventing the translocation step. Tetracyclines have no action on the 23S rRNA. +
Another main mechanism of non-hemolytic febrile transfusion reactions is host antibodies against donor MHC antigens found on leukocytes. This mechanism does not invoke an allergic reaction. It can be preveented by using leukocyte filters or blood irradiation. +
Leuprolide acts as an agonist of luteinizing hormone-releasing hormone (LHRH) causing a disruption of gonadotropin release if given continuously. It is used in the treatment of prostate cancer, endometriosis, and leiomyoma and cannot be used to treat androgenetic alopecia. +
"D" corresponds to the distal convoluted tubule. This is the location where PTH-mediated calcium reabsorption occurs. +
The action stage is defined as an active state of change whereby the patient modifies his behaviors and environment to overcome an addictive behavior. +
These changes may be seen with a decrease in plasma proteins leading to a relative increase in GFR and FF without actual changes in RPF. +