Property:AnswerEExp
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Clindamycin is a second line therapy for CA-MRSA pneumonia in patients that cannot for any reason receive vancomycin or linezolid. +
Quinupristin and Dalfopristin act synergistically to inhibit protein synthesis by inhibiting both peptide bond formation and translocation. +
Acetylation is another form of Rb control. It usually hinders the phosphorylation of pRb by cyclin-dependent kinases to maintain the hypophosphorylated and active form. +
Elastin content is a property of tissue type and is not usually increased in scar tissue. +
This refers to the podocyte foot processes which are usually effaced in MCD and are the cause of the proteinuria. +
This refers to the podocyte foot processes which are usually effaced in minimal change disease. +
LFA-1 integrin or CD18 defect is seen in patient with leukocyte adhesion deficiency type 1 (LAD1), not in WAS. +
Drug adenylation is also a form of enzymatic modification seen in resistance to aminoglycosides not in macrolides. +
This refers to collagen cross-linking via lysyl-oxidase (requires copper). This step is defective in Ehlers-Danlos disease. It is not affected by vitamin C deficiency. +
This refers to collagen cross-linking via lysyl-oxidase (requires copper). This step is the defective step in Ehlers-Danlos disease. +
Biotin functions as a cofactor for carboxylation reactions (Acetyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and propionyl-CoA carboxylase). It has no function with lysyl-oxidase. +
This refers to a podocyte foot process which is usually effaced in minimal change disease and is the cause of the proteinuria. Foot processes are not affected in IgA nephropathy. +
Hydrolysis of conjugated bilirubin is one of the mechanisms of neonatal hyperbilirubinemia. +
Hydrolysis of conjugated bilirubin is one of the mechanisms of neonatal hyperbilirubinemia. +
'''Incorrect''' Ventricular septal defects are characterized by a holosystolic murmur at the lower left sternal border +
'''Incorrect''' Though the initially preferred treatment is medical in mitral regurgitation if ejection fraction drops below 60% and left ventricular end systolic diameter exceeds 40mm, valve repair should be performed +
'''Incorrect''' Endocarditis is often accompanied by fever , and presents as a new murmur or change in an existing murmur. It is diagnosed by blood cultures and vegetations on cardiac valves on echocardiography. The patient in this vignette does not display fever or other acute infective symptoms. +
'''Incorrect''' Ejection fraction <60%, left ventricular end systolic diameter more than 55mm is the operative criteria for mitral regurgitation, not aortic regurgitation +