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Night blindness is one of the first signs of vitamin A deficiency. Vitamin A deficiency is common among patients with malabsorptive conditions, such as Crohn's disease. +
Gene deletion is defined as loss of part of the gene or sequences of the DNA within a chromosome. An example of a disorder caused by large deletions is Duchenne Muscular Dystrophy. +
Cisplatin is a non-cell cycle specific alkylating agent. It inhibits DNA and RNA synthesis by cross-linking DNA strands, thereby causing strand breaks. It is used for genitourinary tumors and is extremely effective for testicular cancers. Adverse events associated with cisplatin administration include ototoxicity and nephrotoxicity. +
Dactinomycin inhibits DNA-dependent RNA polymerase by intercalation between cytosine and guanine nucleotides in DNA and formation of dactinomycin-DNA complexes. +
Rheumatoid arthritis is an autoimmune inflammatory disease characterized by presence of anti-IgG antibodies. Hydroxyurea is not indicated for rheumatoid arthritis. +
Methylene blue and vitamin C are the antidotes for methemoglobin, a hemoglobin with an oxidized form of iron (Fe3+). Methemoglobinemia may be congenital or acquired (usually due to drugs). Patients may present with bluish skin, headache, dyspnea, seizures, and death. +
Mantle cell lymphoma is a rare non-Hodgkin’s lymphoma that affects elderly males. Imatinib is not used to treat Mantle cell lymphoma. +
Dactinomycin inhibits DNA-dependent RNA polymerase by intercalating between cytosine and guanine nucleotides in DNA. +
This is not the correct set of lab results because in patients with POF, ovarian hormones are decreased, while pituitary hormones are increased due to an absence of feedback inhibition. +
Hematologic malignancies, such as lymphomas and leukemias, are not associated with HELLP syndrome and are not a major cause of mortality in these patients. +
The splenic artery is contained in the splenorenal ligament. The splenorenal ligament connects the spleen to the posterior abdominal wall. +
Splenomegaly may be observed among patients with hematological disorders and portal hypertension due to back-up of blood flow in the portal circulation. +
TdT is a protein expressed early in the development of pre-T and pre-B cells but it is not a prognostic marker of the disease. +
''Aspergillus fumigatus'' is a monomorphic filamentous fungus that forms dichotomously branching septate hyphae at 45 degree angle. +
''Rhizopus microsporus'' is on species responsible for mucormycosis. Similar to most zygomycetes it forms broad ribbon-like nonseptate hyphae frequently branching at near right degree angles. +