View source for SEPT3

{{Infobox_gene}}
'''Neuronal-specific septin-3''' is a [[protein]] that in humans is encoded by the ''SEPT3'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SEPT3 septin 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55964| accessdate = }}</ref>

== Function ==

This gene belongs to the [[septin]] family of GTPases. Members of this family are required for [[cytokinesis]]. Expression is upregulated by retinoic acid in a human [[teratocarcinoma]] cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in multiple transcript variants.<ref name="entrez" />

== References ==
{{reflist}}

== Further reading ==
{{refbegin | 2}}
* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 }}
* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = November 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
* {{cite journal | vauthors = Methner A, Leypoldt F, Joost P, Lewerenz J | title = Human septin 3 on chromosome 22q13.2 is upregulated by neuronal differentiation | journal = Biochemical and Biophysical Research Communications | volume = 283 | issue = 1 | pages = 48–56 | date = April 2001 | pmid = 11322766 | doi = 10.1006/bbrc.2001.4741 }}
* {{cite journal | vauthors = Xue J, Milburn PJ, Hanna BT, Graham ME, Rostas JA, Robinson PJ | title = Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals | journal = The Biochemical Journal | volume = 381 | issue = Pt 3 | pages = 753–60 | date = August 2004 | pmid = 15107017 | pmc = 1133885 | doi = 10.1042/BJ20040455 }}
* {{cite journal | vauthors = Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I | title = A genome annotation-driven approach to cloning the human ORFeome | journal = Genome Biology | volume = 5 | issue = 10 | pages = R84 | year = 2005 | pmid = 15461802 | pmc = 545604 | doi = 10.1186/gb-2004-5-10-r84 }}
* {{cite journal | vauthors = Xue J, Tsang CW, Gai WP, Malladi CS, Trimble WS, Rostas JA, Robinson PJ | title = Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals | journal = Journal of Neurochemistry | volume = 91 | issue = 3 | pages = 579–90 | date = November 2004 | pmid = 15485489 | doi = 10.1111/j.1471-4159.2004.02755.x }}
* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = October 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = January 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
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