View source for Cobamamide

{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 447929261
| IUPAC_name = Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-<br>(5'-deoxy-5'-adenosyl)cobamide
| image =Cobamamide.png
| image2 =Cobamamide 3D sticks.png

<!--Clinical data-->
| tradename =  
| Drugs.com = {{drugs.com|international|cobamamide}}
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B            / C / D / X -->
| pregnancy_category =  
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
| legal_US =  OTC  
| legal_status =  
| routes_of_administration =  

<!--Pharmacokinetic data-->
| bioavailability =  
| protein_bound =  
| metabolism =  
| elimination_half-life =  
| excretion =  

<!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 13870-90-1
| ATC_prefix = B03
| ATC_suffix = BA04
| PubChem = 5459907
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =  
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 16736117
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 18408
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00042

<!--Chemical data-->
| C=72 | H=100 | Co=1 | N=18 | O=17 | P=1 
| molecular_weight = 1579.58 g/mol
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31?,34?,35?,36?,37?,41-,52-,53-,56?,57+,59?,60?,61?,62?;4-,6-,7-,10-;/m11./s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ZIHHMGTYZOSFRC-CXGXMSGESA-L
}}
__Notoc__
{{SI}}
{{CMG}}
==Overview==
'''Cobamamide''' (AdoCbl), which is also known as '''adenosylcobalamin''' and '''dibencozide''', is, along with [[methylcobalamin]] (MeCbl), one of the active forms of [[vitamin B12|vitamin B<sub>12</sub>]]. As a nutritional supplement, it is available in tabletted form, but unlike [[cyanocobalamin]], [[methylcobalamin]], and [[hydroxocobalamin]], it is not available in injectable form.

An [[enzyme]] that uses adenosylcobalamin as a [[Cofactor (biochemistry)|cofactor]] is [[methylmalonyl-CoA mutase]] (MCM).

==External links==
* {{ATC|B03|BA04}}

{{biochem-stub}}


{{Vitamin}}
[[Category:B vitamins]]
[[Category:Cofactors]]
[[Category:Vitamin B12]]
[[Category:Drug]]