View source for Chicken ovalbumin upstream promoter-transcription factor

{{infobox protein | Name = [[COUP-TFI|nuclear receptor subfamily 2, group F, member 1]] | caption = | image = | width = | HGNCid = 7975 | Symbol = NR2F1 | AltSymbols = ERBAL3, TFCOUP1, EAR-3, COUP-TFI, TCFCOUP1, SVP44 | EntrezGene = 7025 | OMIM = 132890 | RefSeq = NM_005654 | UniProt = P10589 | PDB = | ECnumber = | Chromosome = 5 | Arm = q | Band = 14 | LocusSupplementaryData = }}

{{infobox protein | Name = [[COUP-TFII|nuclear receptor subfamily 2, group F, member 2]] | caption = | image = | width = | HGNCid = 7976 | Symbol = NR2F2 | AltSymbols = ARP1, TFCOUP2, COUP-TFII, COUPTFB, SVP40 | EntrezGene = 7026 | OMIM = 107773 | RefSeq = NM_021005 | UniProt = P24468 | PDB = | ECnumber = | Chromosome = 15 | Arm = q | Band = 26 | LocusSupplementaryData = }}

The '''chicken ovalbumin upstream promoter transcription factor''' ('''COUP-TF'''s) proteins are members of the [[nuclear receptor]] family of [[intracellular]] [[transcription factor]]s.<ref name="pmid8530078">{{cite journal | vauthors = Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY | title = Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes | journal = Genomics | volume = 29 | issue = 1 | pages = 240–6 | year = 1995 | pmid = 8530078 | doi = 10.1006/geno.1995.1237 }}</ref>  There are two variants of the COUP-TFs, labeled as '''[[COUP-TFI]]''' and '''[[COUP-TFII]]''' encoded by the {{gene|NR2F1}} and {{gene|NR2F2}} genes respectively.

COUP-TFs play critical roles in the development of organisms.<ref name="pmid14529150">{{cite journal | vauthors = Park JI, Tsai SY, Tsai MJ | title = Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actions | journal = The Keio journal of medicine | volume = 52 | issue = 3 | pages = 174–81 | year = 2003 | pmid = 14529150 | doi = 10.2302/kjm.52.174| url = http://www.kjm.keio.ac.jp/past/52/3/174.pdf}}</ref>

== References ==
{{Reflist|2}}

==External links==
* {{MeshName|COUP+Transcription+Factors}}
* {{MeshName|COUP+Transcription+Factor+I}}
* {{MeshName|COUP+Transcription+Factor+II}}

{{Transcription factors|g2}}

[[Category:Intracellular receptors]]
[[Category:Transcription factors]]


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