View source for Café au lait spot

{{Infobox_Disease |
  Name           = {{PAGENAME}} |
  Image          = CALSpot.jpg |
  Caption        = A café au lait spot on a patient's left cheek. |
  DiseasesDB     = 16118 |
  ICD10          = {{ICD10|L|81|3|l|80}} |
  ICD9           = {{ICD9|709.09}} |
  ICDO           = |
  OMIM           = |
  MedlinePlus    = |
  eMedicineSubj  = ped |
  eMedicineTopic = 2754 |
  MeshID         = D019080 |
}}
{{SI}}
{{CMG}}
__NOTOC__
'''Associate Editor-In-Chief:''' {{CZ}}



'''Café au lait spots''' or '''cafe-au-lait spots''' (CAL) are pigmented [[birthmark]]s. 

==Etymology==

The name café au lait is French for "coffee with milk" and refers to their light-brown color in persons with light skin. It will appear as a darker lesion  café noir in people with dark skin.

==Pathophysiology== 

While ''café au lait'' spots are usually not associated with any medical problems, having many (three or more) such spots is linked with [[neurofibromatosis]] and the rare [[McCune-Albright syndrome]]. 

Also, having six or more of such spots greater than 5 mm in diameter prepubertal or greater than 15 mm in diameter postpubertal children is a cardinal diagnostic feature of [[Neurofibromatosis type I]].

==Differential Diagnosis==

Other syndromes that may include Cafe au lait spots:

* [[Fanconi anemia]]
* [[Tuberous sclerosis]]
* [[Russell-Silver syndrome]] ([[Silver-Russell dwarfism]])
* [[Ataxia telangiectasia]]
* [[Bloom syndrome]]
* [[Basal cell nevus syndrome]]
* [[Gaucher disease]]
* [[Chédiak-Higashi syndrome]]
* [[Hunter syndrome]]
* [[Maffucci syndrome]]
* [[Multiple mucosal neuroma syndrome]] ([[Multiple endocrine neoplasia type 2]])




== Diagnosis ==

=== Physical Examination ===
====Skin====
<div align="left">
<gallery heights="175" widths="175">
Image:cafe au lait (NFT1 or NFT2).jpg|Cafe au lait spot<ref>http://picasaweb.google.com/mcmumbi/USMLEIIImages</ref>
Image:cafe au lait (with MR, it's McCune Albright).jpg|Cafe au lait spot (with MR, it's McCune Albright)<ref>http://picasaweb.google.com/mcmumbi/USMLEIIImages</ref>
</gallery>
</div>


==See also==
*[[Birthmark]]
*[[Nevus]]

==References==
{{Reflist}}

==External links==
* [http://www.drgreene.com/21_80.html Dr. Greene]
* [http://www.drhull.com/EncyMaster/C/cafe-au-lait.html Café au lait spots]
* [http://www.emedicine.com/ped/topic2754.htm eMedicine]
* [http://www.emedicine.com/CGI-BIN/FOXWEB.EXE/MAKEZOOM@/EM/MAKEZOOM?FZI=1&PICTURE=\websites\emedicine\ped\images\909470-911900-439.jpg eMedicine image1]
* [http://www.emedicine.com/CGI-BIN/FOXWEB.EXE/MAKEZOOM@/EM/MAKEZOOM?FZI=1&PICTURE=\websites\emedicine\ped\images\909470-911900-376.jpg eMedicine image2]

{{Diseases of the skin and subcutaneous tissue}}

<br>
[[de:Café-au-lait-Fleck]]
[[sr:Флеке боје беле кафе]]
[[pl:Plamy café au lait]]

[[Category:Dermatology]]
[[Category:Medical signs]]
[[Category:Signs and symptoms]]

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