R-CHOP regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Rituximab-Cyclophosphamide-Hydroxydaunorubicin-Oncovin-Prednisone regimen

Overview

R-CHOP regimen refers to an immunochemotherapy regimen consisting of rituximab, cyclophosphamide, hydroxydaunorubicin hydrochloride (doxorubicin hydrochloride), vincristine (Oncovin) and prednisone used to treat both indolent and aggressive forms of non-Hodgkin lymphoma.

Regimen

RRituximab

CCyclophosphamide

HDoxorubicin (Hydroxydaunomycin)

OVincristine (Oncovin)

PPrednisone

Indications

• Diffuse large B-cell lymphoma, untreated
• Mantle cell lymphoma