Adderall

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Synonyms: (+/-)-beta-Phenylisopropylamine, (+/-)-Benzedrine, (+/-)-Desoxynorephedrine, 1-Methyl-2-phenylethylamine, 1-Phenyl-2-aminopropane, 3-Methoxy-a-methylbenzeneethanamine, 3-Methoxyamphetamine, 3-Methoxyphenylisopropylamine, alpha-Methylbenzeneethaneamine, Amphetamine Sulfate, beta-Aminopropylbenzene, dl-1-Phenyl-2-aminopropane, DL-alpha-Methylphenethylamine, dl-Amphetamine, dl-Benzedrine, Fenylo-izopropylaminyl, m-Methoxy-a-methylphenethylamine, m-Methoxyamphetamine, Methamphetamine HCL, [1-(3-Methoxyphenyl)-2-propyl]amine, Phenylisopropylamine, Amfetamine, beta-phenyl-isopropylamine.

Brand Names: Actedron, Adipan, Allodene, Anorexide, Anorexine, Benzebar, Benzedrine, Benzolone, Desoxyn, Dexampex, Dexedrine, Dextrostat, Elastonon, Fenamin, Ferndex, Finam, Isoamycin, Isoamyne, Isomyn, Mecodrin, Methampex, Norephedrane, Novydrine, Oktedrin, Ortedrine, Paredrine, Percomon, Phenamine, Phenedrine, Profamina, Propisamine, Psychedrine, Raphetamine, Rhinalator, Simpatedrin, Simpatina, Sympamin, Sympamine, Sympatedrine, Weckamine.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

Regardless of indication, amphetamines should be administered at the lowest effective dosage and dosage should be individually adjusted according to the therapeutic needs and response of the patient. Late evening doses should be avoided because of the resulting insomnia.

For the treatment of Attention Deficit Hyperactivity Disorder (ADHD): Not recommended for children under 3 years of age. In children from 3 to 5 years of age, start with 2.5 mg daily; daily dosage may be raised in increments of 2.5 mg at weekly intervals until optimal response is obtained.

In children 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.

Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.

For Narcolepsy: Usual dose 5 mg to 60 mg per day in divided doses, depending on the individual patient response.

Narcolepsy seldom occurs in children under 12 years of age; however, when it does, dextroamphetamine sulfate may be used. The suggested initial dose for patients aged 6-12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily; daily dosage may be raised in increments of 10 mg at weekly intervals until optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.



FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español






FDA Package Insert Resources

Indications

Contraindications

Side Effects

Drug Interactions

Precautions

Overdose

Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA label

FDA on Adderall

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Publication Resources

Most Recent Articles on Adderall

Review Articles on Adderall

Articles on Adderall in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Adderall

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Trial Resources

Ongoing Trials with Adderall at Clinical Trials.gov

Trial Results with Adderall

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Adderall

Cochrane Collaboration on Adderall

Cost Effectiveness of Adderall

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Media Resources

Powerpoint Slides on Adderall

Images of Adderall

Podcasts & MP3s on Adderall

Videos on Adderall

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Patient Resources

Patient Resources on Adderall

Discussion Groups on Adderall

Patient Handouts on Adderall

Blogs on Adderall

Adderall in the News

Adderall in the Marketplace

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International Resources

Adderall en Español

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Adapted from the FDA Package Insert.