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	<updated>2026-04-09T15:56:28Z</updated>
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		<id>https://www.wikidoc.org/index.php?title=MYH4&amp;diff=1529304</id>
		<title>MYH4</title>
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		<updated>2018-09-20T04:02:55Z</updated>

		<summary type="html">&lt;p&gt;2601:281:8200:8961:58D2:E5B2:A6DA:7E30: /* Function */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;{{Infobox_gene}}&lt;br /&gt;
&lt;br /&gt;
&#039;&#039;&#039;Myosin-4&#039;&#039;&#039; also known as &#039;&#039;&#039;myosin, heavy chain 4&#039;&#039;&#039; is a [[protein]] which in humans is encoded by the &#039;&#039;MYH4&#039;&#039; [[gene]].&amp;lt;ref name=&amp;quot;pmid3000272&amp;quot;&amp;gt;{{cite journal |vauthors=Edwards YH, Parkar M, Povey S, West LF, Parrington JM, Solomon E | title = Human myosin heavy chain genes assigned to chromosome 17 using a human cDNA clone as probe | journal = Ann. Hum. Genet. | volume = 49 | issue = Pt 2 | pages = 101–9 |date=May 1985 | pmid = 3000272 | doi = 10.1111/j.1469-1809.1985.tb01681.x| url = | issn = }}&amp;lt;/ref&amp;gt;&lt;br /&gt;
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== Function ==&lt;br /&gt;
&lt;br /&gt;
MYH4 is a gene that encodes a sarcomeric myosin.&lt;br /&gt;
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== References ==&lt;br /&gt;
{{Reflist}}&lt;br /&gt;
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==Further reading==&lt;br /&gt;
{{refbegin | 2}}&lt;br /&gt;
*{{cite journal   |vauthors=Sant&#039;ana Pereira JA, Wessels A, Nijtmans L, etal |title=New method for the accurate characterization of single human skeletal muscle fibres demonstrates a relation between mATPase and MyHC expression in pure and hybrid fibre types. |journal=J. Muscle Res. Cell. Motil. |volume=16 |issue= 1 |pages= 21–34 |year= 1995 |pmid= 7751402 |doi=10.1007/BF00125307  }}&lt;br /&gt;
*{{cite journal   |vauthors=Weiss A, McDonough D, Wertman B, etal |title=Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 6 |pages= 2958–63 |year= 1999 |pmid= 10077619 |doi=  10.1073/pnas.96.6.2958|pmc=15877  }}&lt;br /&gt;
*{{cite journal  |vauthors=Barton PJ, Buckingham ME |title=The myosin alkali light chain proteins and their genes. |journal=Biochem. J. |volume=231 |issue= 2 |pages= 249–61 |year= 1985 |pmid= 3904738 |doi=  |pmc=1152739  }}&lt;br /&gt;
*{{cite journal   |vauthors=Horton MJ, Brandon CA, Morris TJ, etal |title=Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres. |journal=Arch. Oral Biol. |volume=46 |issue= 11 |pages= 1039–50 |year= 2001 |pmid= 11543711 |doi=10.1016/S0003-9969(01)00066-8  |pmc=3848045 }}&lt;br /&gt;
*{{cite journal  |vauthors=Weiss A, Schiaffino S, Leinwand LA |title=Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. |journal=J. Mol. Biol. |volume=290 |issue= 1 |pages= 61–75 |year= 1999 |pmid= 10388558 |doi= 10.1006/jmbi.1999.2865 }}&lt;br /&gt;
*{{cite journal  |vauthors=Larsson L, Moss RL |title=Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. |journal=J. Physiol. |volume=472 |issue=  |pages= 595–614 |year= 1993 |pmid= 8145163 |doi=  10.1113/jphysiol.1993.sp019964|pmc=1160504  }}&lt;br /&gt;
*{{cite journal  |vauthors=Li ZH, Spektor A, Varlamova O, Bresnick AR |title=Mts1 regulates the assembly of nonmuscle myosin-IIA. |journal=Biochemistry |volume=42 |issue= 48 |pages= 14258–66 |year= 2003 |pmid= 14640694 |doi= 10.1021/bi0354379 }}&lt;br /&gt;
*{{cite journal  |vauthors=Sowa ME, Bennett EJ, Gygi SP, Harper JW |title=Defining the human deubiquitinating enzyme interaction landscape. |journal=Cell |volume=138 |issue= 2 |pages= 389–403 |year= 2009 |pmid= 19615732 |doi= 10.1016/j.cell.2009.04.042  |pmc=2716422 }}&lt;br /&gt;
*{{cite journal   |vauthors=Ford HL, Silver DL, Kachar B, etal |title=Effect of Mts1 on the structure and activity of nonmuscle myosin II. |journal=Biochemistry |volume=36 |issue= 51 |pages= 16321–7 |year= 1997 |pmid= 9405067 |doi= 10.1021/bi971182l }}&lt;br /&gt;
*{{cite journal  |vauthors=Soussi-Yanicostas N, Whalen RG, Petit C |title=Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome. |journal=Hum. Mol. Genet. |volume=2 |issue= 5 |pages= 563–9 |year= 1993 |pmid= 8518795 |doi=10.1093/hmg/2.5.563  }}&lt;br /&gt;
*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  |pmc=1847948 }}&lt;br /&gt;
{{refend}}&lt;br /&gt;
&lt;br /&gt;
{{PDB Gallery|geneid=4622}}&lt;br /&gt;
{{Cytoskeletal Proteins}}&lt;br /&gt;
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{{gene-17-stub}}&lt;/div&gt;</summary>
		<author><name>2601:281:8200:8961:58D2:E5B2:A6DA:7E30</name></author>
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