Zofenopril

Zofenopril
Clinical data
Routes of; administration	Oral
ATC code	C09AA15 (WHO) ;
Identifiers
	IUPAC name (2S,4S)-1-[(2S)-3-(Benzoylsulfanyl)-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid;
CAS Number	81872-10-8;
PubChem CID	92400;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C22H23NO4S2
Molar mass	429.552 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Sheng Shi, M.D. [2]

Zofenopril (also known as Zofenoprilum [Latin]) is an angiotensin converting enzyme (ACE) inhibitor with cardioprotective properties indicated for the treatment of hypertension.^[1]

In small studies, zofenopril appeared significantly more effective than the older antihypertensives atenolol and enalapril, and was associated with less adverse effects.^[2]^[3]

References

↑ Ambrosioni E (2007). "Defining the role of zofenopril in the management of hypertension and ischemic heart disorders". Am J Cardiovasc Drugs. 7 (1): 17–24. doi:10.2165/00129784-200707010-00002. PMID 17355163.
↑ Nilsson P (October 2007). "Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension". Blood Press Suppl. 2: 25–30. PMID 18046976.
↑ Mallion JM (October 2007). "An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension". Blood Press Suppl. 2: 13–8. PMID 18046974.

Clinical data

Routes of administration	Oral
ATC code	C09AA15 (WHO)
Identifiers
IUPAC name (2S,4S)-1-[(2S)-3-(Benzoylsulfanyl)-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid
CAS Number	81872-10-8
PubChem CID	92400
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₂H₂₃NO₄S₂
Molar mass	429.552 g/mol