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==Treatment==
==Treatment==
There are two schools of thought as to the best therapy for Wilms' tumor.
The National Wilms' Tumor Study (NWTS) has been studying this tumor in the United States since 1969. This group recommends surgery as the primary therapy for Wilms' tumor. They have carried out extensive research on this tumor which has been used to guide therapy, as well as to classify tumors into high and low risk groups based on molecular features and to estimate prognosis.
The International Society of Paediatric Oncology in Europe, on the other hand, recommends preoperative chemotherapy to downstage the tumor prior to surgery to reduce the risk of intraoperative rupture of the tumor and dissemination of the malignant cells. A 4 week period of preoperative chemotherapy decreases the risk of intraoperative rupture of the tumor.
[[Wilms' tumor medical therapy|Medical Therapy]] | [[Wilms' tumor surgery|Surgery]] | [[Wilms' tumor cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Wilms' tumor future or investigational therapies|Future or Investigational Therapies]]
[[Wilms' tumor medical therapy|Medical Therapy]] | [[Wilms' tumor surgery|Surgery]] | [[Wilms' tumor cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Wilms' tumor future or investigational therapies|Future or Investigational Therapies]]
==Case Studies==
==Case Studies==
:[[Wilms' tumor case study one|Case #1]]
:[[Wilms' tumor case study one|Case #1]]

Revision as of 11:22, 14 January 2015

Wilms' tumor
ICD-10 C64
ICD-9 189.0
ICD-O: Template:ICDO
OMIM 194070 607102
DiseasesDB 8896
MeSH D009396

Wilms' tumor Microchapters

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Case #1

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For patient information click here

Steven C. Campbell, M.D., Ph.D.; Assistant Editor-in-Chief: Savni Satoskar

Synonyms and keywords: Nephroblastoma

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Wilms' tumor from other Diseases

Epidemiology and Demographics

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI | Ultrasound | Other Diagnostic Studies

Treatment

There are two schools of thought as to the best therapy for Wilms' tumor.

The National Wilms' Tumor Study (NWTS) has been studying this tumor in the United States since 1969. This group recommends surgery as the primary therapy for Wilms' tumor. They have carried out extensive research on this tumor which has been used to guide therapy, as well as to classify tumors into high and low risk groups based on molecular features and to estimate prognosis.

The International Society of Paediatric Oncology in Europe, on the other hand, recommends preoperative chemotherapy to downstage the tumor prior to surgery to reduce the risk of intraoperative rupture of the tumor and dissemination of the malignant cells. A 4 week period of preoperative chemotherapy decreases the risk of intraoperative rupture of the tumor.



Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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