WBR0507

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Author [[PageAuthor::Gonzalo A. Romero, M.D. (Reviewed by Alison Leibowitz)(Reviewed by Serge Korjian)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Embryology, MainCategory::Microbiology, MainCategory::Pharmacology
Sub Category SubCategory::Infectious Disease
Prompt [[Prompt::A 2-year-old girl is brought to the pediatrician because her mother is concerned that her teeth have turned a dark shade of gray since her last check-up. The mother explains that her daughter has been developing normally, but she recently started refusing formula. She also reports that approximately 2 months ago, the child had an episode of cough and sore throat for which she gave her some left-over antibiotics she had at home. Physical exam is unremarkable except for dark gray stains apparent mostly across the front teeth. Which of the following is a property of the drug used in this patient?]]
Answer A AnswerA::Prevents attachment of aminoacyl-tRNA to 30S ribosomal subunit
Answer A Explanation AnswerAExp::Tetracycline
Answer B AnswerB::Inhibits the formation of initiation complex
Answer B Explanation AnswerBExp::Aminoglycosides
Answer C AnswerC::Inhibits protein synthesis by binding to the 50S ribosomal subunit
Answer C Explanation AnswerCExp::Clindamycin
Answer D AnswerD::Inhibits the translocation by binding to the 23S ribosomal subunit
Answer D Explanation AnswerDExp::Macrolide
Answer E AnswerE::Inhibits protein elongation by blocking peptidyl-transferase
Answer E Explanation AnswerEExp::Chloram
Right Answer RightAnswer::A
Explanation [[Explanation::

Educational Objective:
References: ]]

Approved Approved::Yes
Keyword
Linked Question Linked::
Order in Linked Questions LinkedOrder::