WBR0115

Author	[[PageAuthor::Yazan Daaboul, M.D.]]
Exam Type	ExamType::USMLE Step 1
Main Category	MainCategory::Microbiology
Sub Category	SubCategory::Infectious Disease
Prompt	[[Prompt::During an outbreak of an infectious disease, a 30-year-old man presents to the emergency department with fever for the past 2 days. He complains that he has diffuse body aches with myalgia and loss of appetite. Further history-taking reveals that the patient was recently bitten by a Culex mosquito. The patient's blood pressure is 110/84 mmHg, heart rate is 102/min, and temperature is 38.4 °C (101.12 °F). Physical examination, including neurological exam, is unremarkable. The physician suspects the patient might be infected by an agent that has also infected bird species in the same district. Which of the following best characterizes the infectious agent responsible for this patient's condition?]]
Answer A	AnswerA::Enveloped single-stranded positive-sense RNA virus
Answer A Explanation	AnswerAExp::West Nile virus is an enveloped single-stranded positive-sense RNA virus.
Answer B	AnswerB::Enveloped single-stranded negative-sense RNA virus
Answer B Explanation	AnswerBExp::West Nile virus is not an enveloped single-stranded negative-sense RNA virus. Examples of enveloped single-stranded negative-sense RNA virus include influenza virus, parainfluenza virus, RSV, mumps, measles, and rabies.
Answer C	AnswerC::Non-enveloped single-stranded positive-sense RNA virus
Answer C Explanation	AnswerCExp::West Nile virus is not a non-enveloped single-stranded positive-sense RNA virus. Examples of non-enveloped single-stranded positive-sense RNA viruses include norovirus, HEV, and picornaviruses.
Answer D	AnswerD::Non-enveloped single-stranded negative-sense RNA virus
Answer D Explanation	AnswerDExp::West Nile virus is not a non-enveloped single-stranded negative-sense RNA virus. Most single-stranded negative-sense RNA virus are enveloped, such as influenza virus, , parainfluenza virus, RSV, mumps, measles, and rabies.
Answer E	AnswerE::Non-enveloped double-stranded RNA virus
Answer E Explanation	AnswerEExp::West Nile virus is not a non-enveloped double-stranded RNA virus. Examples of non-enveloped double-stranded RNA virus include reoviruses, such as coltivirus and rotavirus.
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Approved	Approved::No
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