Ventricular tachycardia epidemiology and demographics
- Sustained ventricular tachycardia (VT) is an important cause of 150,000 to 300,000 out of hospital sudden deaths that occur annually in the US.[1]
- The most common cause of wide complex tachycardia(WCT) is ventricular tachycardia (VT), which accounts for 80% of all cases of WCT.[2]
- Supraventricular tachycardia (SVT) with aberrancy accounts for 15% to 20% of WCTs. SVTs with bystander preexcitation and antidromic atrioventricular reentrant tachycardia (AVRT) account for 1% to 6% of WCTs.[3]
- However, the underlying substrate varies: ischemic heart disease in 75–80% cases; idiopathic cardiomyopathy in 10–15%; and 1–2% due to rare monogenic mutations in cardiac ion channels or associated proteins.4
- Brugada Syndrome may account for up to 50% of all [[SCD]s in young individuals without structural heart disease. 4
- The prevalence of nonsustained VT detected by 24-hour Ambulatory ECGs was 4% in 98 elderly, disease-free individuals in the Baltimore Longitudinal Study of Aging,5 4% in 106 active elderly people,6 2% in 50 elderly people without cardiovascular disease,7 4% in 729 elderly women and 13% in 643 elderly men in the Cardiovascular Health Study,8 3% in 135 elderly men and 2% in 297 elderly women without cardiovascular disease,9 9% in 385 elderly men and 8% in 806 elderly women with hypertension, valvular disease, or cardiomyopathy,9 6% in 395 elderly men and 15% in 771 elderly women with coronary artery disease (CAD),9 and 5% in a well population of 80 year olds in the Bronx Longitudinal Aging Study.10
- The prevalence of complex ventricular arrhythmia in elderly people in these studies was 50%,5 31%,6 20%,7 16% in women and 28% in men,8 31% in men and 30% in women without cardiovascular disease,9 54% in men and 55% in women with hypertension, valvular disease, or cardiomyopathy,9 and 69% in men and 68% in women with CAD.9
- ↑ Stevenson WG (2009). "Ventricular scars and ventricular tachycardia". Trans Am Clin Climatol Assoc. 120: 403–12. PMC 2744510. PMID 19768192.
- ↑ Gupta AK, Thakur RK (2001). "Wide QRS complex tachycardias". Med Clin North Am. 85 (2): 245–66, ix–x. PMID 11233948.
- ↑ Issa Z, Miller JM, Zipes DP(2009). Approach to Wide QRS Complex Tachycardias. Arrhythmology and Electrophysiology: A Companion to Braunwald's heart disease (1st ed., pp. 393). Philadelphia, Pa: Saunders Elsevier.