Ventilation-perfusion mismatch

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Template:Ventilation-perfusion mismatch Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ventilation Perfusion (V/Q) mismatch is said to have occurred when there is a there is defect in alveolar gas exchange in the lung either due to poor perfusion or reduced air entry. In common practice, the term applies mostly to describe conditions that includes the former (poor perfusion)[1]

In ideal physiologic conditions, V/Q ratio should be 1, that is 100 percent of the alveoli are recruited (full air entry), good oxygenation and 100 percent of the alveolar capillaries are perfused. However this does not happen even in healthy individuals as not all the alveoli in a healthy lung are recruited. The normal V/Q ratio is estimated to be 0.8.

Causes

Pathophysiology

References

  1. Petersson, J. "Gas exchange and ventilation-perfusion relationships in the lung". Eur Respir J.