Urethral cancer natural history, complications, and prognosis: Difference between revisions
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* In men, the prognosis of tumors in the distal (pendulous) urethra is better than for tumors of the proximal (bulbomembranous) and prostatic urethra, which tend to present at more advanced stages. | * In men, the prognosis of tumors in the distal (pendulous) urethra is better than for tumors of the proximal (bulbomembranous) and prostatic urethra, which tend to present at more advanced stages. | ||
* Distal urethral tumors tend to occur at earlier stages in women, and they appear to have a better prognosis than proximal tumors. | * Distal urethral tumors tend to occur at earlier stages in women, and they appear to have a better prognosis than proximal tumors. | ||
* Lesions of the proximal or entire length of the urethra are usually associated with invasion and a high incidence of pelvic nodal metastases with 5-year survival rates ranging from 10% to 20%. | |||
==References== | ==References== |
Revision as of 18:31, 8 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The prognosis varies with the depth of invasion, anatomical location, size, and stage of tumor. Superficial tumors located in the distal urethra have the most favorable prognosis.
Prognosis
- The prognosis of urethral cancer depends on the following factors:[1]
- Anatomical location
- Size
- Stage
- Depth of invasion
- Superficial tumors located in the distal urethra of both the female and male are generally curable. However, deeply invasive lesions are rarely curable by any combination of therapies.
- In men, the prognosis of tumors in the distal (pendulous) urethra is better than for tumors of the proximal (bulbomembranous) and prostatic urethra, which tend to present at more advanced stages.
- Distal urethral tumors tend to occur at earlier stages in women, and they appear to have a better prognosis than proximal tumors.
- Lesions of the proximal or entire length of the urethra are usually associated with invasion and a high incidence of pelvic nodal metastases with 5-year survival rates ranging from 10% to 20%.
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq