Typhoid fever history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

History

Symptoms

Symptoms of typhoid fever include the following:

Most common symptoms

Less common symptoms

  • Rash causing flat, rose-colored spots [2]

Course of typhoid fever

Typhoid fever symptoms can be divided into four individual stages, each lasting approximately one week.

First week

  • Slowly rising temperature with relative bradycardia,
  • malaise
  • headache
  • cough.
  • Epistaxis
  • abdominal pain

Second week

  • Prostration
  • High grade fever which plateaus around 40°C
  • Bradycardia (Sphygmo-thermic dissociation), classically with a dicrotic pulse wave.
  • Delirium or agitation (nervous fever)
  • Rose spots on the lower chest and abdomen(1/3 patients).
  • Rhonchi in lung bases.
  • Painful abdomen(right lower quadrant).
  • Diarrhea (six to eight stools/day), green with a characteristic smell, comparable to pea-soup.
  • Constipation

Third week

References

  1. STUART BM, PULLEN RL (1946). "Typhoid; clinical analysis of 360 cases". Arch Intern Med (Chic). 78 (6): 629–61. PMID 20278487.
  2. "CDC Typhoid Fever". Center for Disease Control. 2005-10-25. Retrieved 2007-10-02.

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