Tularemia differential diagnosis: Difference between revisions

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==Differentiating Tularemia from other Tick-borne diseases==
==Differentiating Tularemia from other Tick-borne diseases==
The following table differentiates between variations of tularemia and their associated manifestations.
{| style="font-size: 85%;"
! style="width: 80px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Clinical Manifestation}}
! style="width: 720px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Transmission}}
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" | Ulceroglandular
| style="background: #DCDCDC; padding: 5px;" |Transmitted by the bite of an infected tick or deer fly
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Glandular
| style="background: #DCDCDC; padding: 5px;" | Transmitted by the bite of an infected tick or deer fly, however skin ulcer does not form.
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Oculoglandular
| style="background: #DCDCDC; padding: 5px;" | Transmitted through eye contact with infected animal meat. Either through rubbing of the eyes during the butchering process or fluid exposure.
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Pneumonic
| style="background: #DCDCDC; padding: 5px;" | Most dangerous form of tularemia, commonly transmitted through inhalation of material infected with the organism. May also occur if a tularemia infection is left untreated and spreads through the blood streams to the lungs. 
|-
|} <ref name= "Signs Sym"> Centers for Disease Control and Prevention, Signs and Symptoms of Tularemia. http://www.cdc.gov/tularemia/signssymptoms/index.html Accessed March 1, 2016 </ref>
The following table differentiates between general symptoms associated with tularemia and other similarly presenting, tick borne diseases.
{| style="font-size: 85%;"
{| style="font-size: 85%;"
! style="width: 80px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Disease}}
! style="width: 80px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Disease}}
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| style="background: #DCDCDC; padding: 5px;" |Non-specific flu like symptoms.
| style="background: #DCDCDC; padding: 5px;" |Non-specific flu like symptoms.
|}
|}
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 15:08, 1 March 2016


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ilan Dock, B.S.

Overview

General symptoms reported within the early stages tularemia often resemble those of other tick-borne diseases. These symptoms include fever, chills, headache, and other non-specific flu like symptoms. Later stages of tularemia may include pneumonic clinical manifestations and ulcers in the epidermal tissue. [1]

Differentiating Tularemia from other Tick-borne diseases

The following table differentiates between variations of tularemia and their associated manifestations.

Clinical Manifestation Transmission
Ulceroglandular Transmitted by the bite of an infected tick or deer fly
Glandular Transmitted by the bite of an infected tick or deer fly, however skin ulcer does not form.
Oculoglandular Transmitted through eye contact with infected animal meat. Either through rubbing of the eyes during the butchering process or fluid exposure.
Pneumonic Most dangerous form of tularemia, commonly transmitted through inhalation of material infected with the organism. May also occur if a tularemia infection is left untreated and spreads through the blood streams to the lungs.

[1]


The following table differentiates between general symptoms associated with tularemia and other similarly presenting, tick borne diseases.

Disease Symptoms
Bacterial Infection
Borreliosis (Lyme Disease) [2] Flu-like illness, fatigue, fever, arthritis, neuroborreliosis, cranial nerve palsy, carditis and erythema migrans.
Relapsing Fever [3] Consistently documented high fevers, flu-like illness, headaches, muscular soreness or joint pain, altered mental state, painful urination, rash, and rigors.
Typhus (Rickettsia)
Rocky Mountain Spotted Fever Fever, alterations in mental state, myalgia, rash, and headaches.
Helvetica Spotted Fever [4] Rash: spotted, red dots. Respiratory symptoms (dyspnea, cough), muscle pain, and headaches.
Ehrlichiosis Anaplasmosis [5] Fever, headache, chills, malaise, muscle pain, nausea, confusion, conjunctivitis, or rash (60% in children and 30% in adults).
Tularemia [6] Ulceroglandular, Glandular, Oculoglandular, Oroglandular, Pneumonic, Typhoidal.
Viral Infection
Tick-borne meningoencephalitis [7] Early Phase: Non-specific symptoms including fever, malaise, anorexia, muscle pains, headaches, nausea, and vomiting. Second Phase: Meningitis symptoms, headache, stiff neck, encephalitis, drowsiness, sensory disturbances, and potential paralysis.
Colorado Tick Fever [8] Common symptoms include fever, chills, headache, body aches, and lethargy. Other symptoms associated with the disease include sore throat, abdominal pain, vomiting, and a skin rash. A biphasic fever is a hallmark of Colorado Tick Fever and presents itself in nearly 50% of infected patients.
Crimean-Congo Hemorrhagic Fever Initially infected patients will likely feel a few of the following symptoms; headache, high fever, back and joint pain, stomach pain, vomiting, flushed face, red throat petechiae of the palate, and potentially changes in mood as well as sensory perception.
Protozoan Infection
Babesiosis [9] Non-specific flu like symptoms.

References

  1. 1.0 1.1 Centers for Disease Control and Prevention, Signs and Symptoms of Tularemia. http://www.cdc.gov/tularemia/signssymptoms/index.html Accessed March 1, 2016
  2. Lyme Disease Information for HealthCare Professionals. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/lyme/healthcare/index.html Accessed on December 30, 2015
  3. Relapsing Fever Information. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/relapsing-fever/ Accessed on December 30, 2015
  4. Rocky Mountain Spotted Fever Information. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/rmsf/ Accessed on December 30, 2015
  5. Disease index General Information (2015). http://www.cdc.gov/parasites/babesiosis/health_professionals/index.html Accessed on December 30, 2015
  6. Rocky Mountain Spotted Fever Information. Centers for Disease Control and Prevention (2015). \http://www.cdc.gov/tularemia/index.html Accessed on December 30, 2015
  7. General Disease Information (TBE). Centers for Disease Control and Prevention (2015). http://www.cdc.gov/vhf/tbe/ Accessed on December 30, 2015
  8. General Tick Deisease Information. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/coloradotickfever/index.html Accessed on December 30, 2015
  9. Babesiosis. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/parasites/babesiosis/disease.htmlAccessed December 8, 2015.

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