Transitional cell carcinoma risk factors: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(10 intermediate revisions by 2 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Transitional cell carcinoma}}
{{Transitional cell carcinoma}}
{{CMG}};{{AE}} {{PSK}}
{{CMG}};{{AE}} {{PSK}}{{AG}}
==Overview==
==Overview==
Common risk factors in the development of transitional cell carcinoma are [[smoking]], occupational exposure to chemicals, chronic bladder irritation, [[chemotherapy]], [[radiation therapy]], [[arsenic]], personal history of cancer in the [[urinary tract]], [[congenital]] bladder anomalies, and aristolochic acids.
Common risk factors in the development of [[Transitional cell bladder carcinoma|transitional cell carcinoma]] are [[smoking]], occupational exposure to [[chemicals]], chronic [[bladder]] irritation, [[chemotherapy]], [[radiation therapy]], [[arsenic]], personal history of [[Cancer (disease)|cancer]] in the [[urinary tract]], [[congenital]] [[Bladder|bladder anomalies]], and [[Aristolochic acid|aristolochic acids]].


== Risk Factors ==
== Risk Factors ==
Environmental exposures account for most cases of bladder cancer.
Environmental exposures account for most cases of [[bladder cancer]].
 
Common [[Risk factor|risk factors]] in the development of [[transitional cell carcinoma]] are:<ref name="Canada">Risk factors for bladder cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/renal-pelvis-and-ureter/risks/?region=ab Accessed on February 10, 2016 </ref><ref name="KirkaliTuzel2003">{{cite journal|last1=Kirkali|first1=Ziya|last2=Tuzel|first2=Emre|title=Transitional cell carcinoma of the ureter and renal pelvis|journal=Critical Reviews in Oncology/Hematology|volume=47|issue=2|year=2003|pages=155–169|issn=10408428|doi=10.1016/S1040-8428(03)00079-9}}</ref><ref name="pmid21846855">{{cite journal| author=Freedman ND, Silverman DT, Hollenbeck AR, Schatzkin A, Abnet CC| title=Association between smoking and risk of bladder cancer among men and women. | journal=JAMA | year= 2011 | volume= 306 | issue= 7 | pages= 737-45 | pmid=21846855 | doi=10.1001/jama.2011.1142 | pmc=3441175 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21846855  }}</ref><ref name="pmid26149669">{{cite journal| author=Cumberbatch MG, Rota M, Catto JW, La Vecchia C| title=The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks. | journal=Eur Urol | year= 2016 | volume= 70 | issue= 3 | pages= 458-66 | pmid=26149669 | doi=10.1016/j.eururo.2015.06.042 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26149669  }}</ref><ref name="pmid14750529">{{cite journal| author=Kogevinas M, 't Mannetje A, Cordier S, Ranft U, González CA, Vineis P et al.| title=Occupation and bladder cancer among men in Western Europe. | journal=Cancer Causes Control | year= 2003 | volume= 14 | issue= 10 | pages= 907-14 | pmid=14750529 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14750529  }}</ref><ref name="pmid17671226">{{cite journal| author=Jiang X, Yuan JM, Skipper PL, Tannenbaum SR, Yu MC| title=Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County. | journal=Cancer Res | year= 2007 | volume= 67 | issue= 15 | pages= 7540-5 | pmid=17671226 | doi=10.1158/0008-5472.CAN-07-0048 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17671226  }}</ref>


Common risk factors in the development of transitional cell carcinoma are:<ref name="Canada">Risk factors for bladder cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/renal-pelvis-and-ureter/risks/?region=ab Accessed on February 10, 2016 </ref><ref name="KirkaliTuzel2003">{{cite journal|last1=Kirkali|first1=Ziya|last2=Tuzel|first2=Emre|title=Transitional cell carcinoma of the ureter and renal pelvis|journal=Critical Reviews in Oncology/Hematology|volume=47|issue=2|year=2003|pages=155–169|issn=10408428|doi=10.1016/S1040-8428(03)00079-9}}</ref>
*[[Smoking]]
*[[Smoking]]
:*Smoking tobacco is the strongest risk factor for developing cancer of the renal pelvis or ureter.
**[[Smoking]] [[tobacco]] is the strongest risk factor for developing [[cancer]] of the r[[Renal pelvis|enal pelvis]] or [[ureter]].
:*Risk increases with the length of time a person smokes and with the number of cigarettes smoked.
**Risk increases with the length of time a person [[smokes]] and with the number of [[cigarettes]] smoked.
*Exposure to [[secondhand smoke]]
*[[Phenacetin]]
*[[Phenacetin]]
*Aromatic amines, such as 2-naphthylamine, benzidine.
*[[Aromatic amines]], such as 2[[Naphthylamine|-naphthylamine]], [[benzidine]]
*[[Human papilloma virus]]
*[[Human papilloma virus]]
*[[Balkan nephropathy]]
*[[Balkan nephropathy]]
*Well-characterized carcinogenic chemicals
*Well-characterized [[carcinogenic]] chemicals
 
** 4-aminobiphenyl
* 4-aminobiphenyl,
** 4-nitrobiphenyl
* 4-nitrobiphenyl,
** 2-amino-1-naphthol
* 2-amino-1-naphthol
*Occupational exposure to [[chemicals]]
:*[[Metal]] workers
:* Painters
:* Rubber industry workers
:* Textile and electrical workers
:* Miners
:* Cement workers
:* Transport operators
:* Excavating-machine operators
:* Jobs that involve the manufacture of carpets, paints, plastics, and industrial chemicals.
* Chronic [[bladder]] irritation
* Drinking chlorinated [[water]]
* High concentrations of [[arsenic]] in drinking water
* Decreased fluid intake
* Consumption of Chinese herbs that contain [[aristolochic acid]]
*[[Inflammation]]
*Chronic [[urinary tract infection]]
*[[Bladder stones]]
*''[[Schistosoma haematobium]]''


*Occupational exposure to chemicals
*[[Trauma]]
:* Textiles
:* Rubber
:* Paint
:* Leather
:* Dye
:* Print
:* Metal
:* Machining
:* Plastics
:* Transportation
* Chronic [[bladder]] irritation
:* [[Inflammation]]
::* Chronic [[urinary tract infection]]
::* [[Bladder stones]]
::* ''[[Schistosoma haematobium]]''
:* Trauma
* [[Chemotherapy]]
* [[Chemotherapy]]
:* [[Cyclophosphamide]]
:* [[Cyclophosphamide]]
Line 44: Line 48:
* [[Radiation therapy]]
* [[Radiation therapy]]
* [[Arsenic]]
* [[Arsenic]]
* Personal history of cancer in the [[urinary tract]]
* [[Congenital]] [[bladder anomalies]]
* [[Congenital]] bladder anomalies
:*[[Urachus]]
:*[[Urachus]]
:*[[Bladder exstrophy|Exstrophy]]
:*[[Bladder exstrophy|Exstrophy]]
* Aristolochic acids
*[[Urothelial cancer|Urothelial cancers]] of the [[renal pelvis]] and [[ureter]]
* Augmentation [[cystoplasty]]
*[[Thiazolidinediones]] given for [[Diabetes mellitus|diabetes]]
* Other factors
:* Air pollution
:*[[Artificial sweetener|Artificial sweeteners]]
:* Coffee and tea
:* Hair dyes
*[[Genetic]] effects
:*[[Hereditary]]
:*[[Mutations|Mutation]] in the [[TP53 (gene)|TP53 gene]]
:* Alterations of the [[Rb|RB gene]]
:* Differences in the endogenous mechanisms responsible for metabolizing chemical [[carcinogens]]


==References==
==References==

Latest revision as of 17:10, 11 November 2019

Transitional cell carcinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Transitional cell carcinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Cystoscopy and Bladder Biopsy

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Transitional cell carcinoma risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Transitional cell carcinoma risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Transitional cell carcinoma risk factors

CDC on Transitional cell carcinoma risk factors

Transitional cell carcinoma risk factors in the news

Blogs on Transitional cell carcinoma risk factors

Directions to Hospitals Treating Transitional cell carcinoma

Risk calculators and risk factors for Transitional cell carcinoma risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]Anthony Gallo, B.S. [3]

Overview

Common risk factors in the development of transitional cell carcinoma are smoking, occupational exposure to chemicals, chronic bladder irritation, chemotherapy, radiation therapy, arsenic, personal history of cancer in the urinary tract, congenital bladder anomalies, and aristolochic acids.

Risk Factors

Environmental exposures account for most cases of bladder cancer.

Common risk factors in the development of transitional cell carcinoma are:[1][2][3][4][5][6]

  • Metal workers
  • Painters
  • Rubber industry workers
  • Textile and electrical workers
  • Miners
  • Cement workers
  • Transport operators
  • Excavating-machine operators
  • Jobs that involve the manufacture of carpets, paints, plastics, and industrial chemicals.

References

  1. Risk factors for bladder cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/renal-pelvis-and-ureter/risks/?region=ab Accessed on February 10, 2016
  2. Kirkali, Ziya; Tuzel, Emre (2003). "Transitional cell carcinoma of the ureter and renal pelvis". Critical Reviews in Oncology/Hematology. 47 (2): 155–169. doi:10.1016/S1040-8428(03)00079-9. ISSN 1040-8428.
  3. Freedman ND, Silverman DT, Hollenbeck AR, Schatzkin A, Abnet CC (2011). "Association between smoking and risk of bladder cancer among men and women". JAMA. 306 (7): 737–45. doi:10.1001/jama.2011.1142. PMC 3441175. PMID 21846855.
  4. Cumberbatch MG, Rota M, Catto JW, La Vecchia C (2016). "The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks". Eur Urol. 70 (3): 458–66. doi:10.1016/j.eururo.2015.06.042. PMID 26149669.
  5. Kogevinas M, 't Mannetje A, Cordier S, Ranft U, González CA, Vineis P; et al. (2003). "Occupation and bladder cancer among men in Western Europe". Cancer Causes Control. 14 (10): 907–14. PMID 14750529.
  6. Jiang X, Yuan JM, Skipper PL, Tannenbaum SR, Yu MC (2007). "Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County". Cancer Res. 67 (15): 7540–5. doi:10.1158/0008-5472.CAN-07-0048. PMID 17671226.

Template:WH Template:WS