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==History and Symptoms==
==History and Symptoms==
In general symptoms of toxic shock syndrome vary depending on the underlying cause. In either case, diagnosis is based strictly upon CDC criteria modified in 1981 after the initial surge in tampon-associated infections<ref>http://wonder.cdc.gov/wonder/prevguid/m0025629/m0025629.asp#head001e00000000000</ref>. TSS resultant of infection with the bacteria ''Staphylococcus aureus'' typically manifests in otherwise healthy individuals with high [[fever]], accompanied by low [[blood pressure]], [[malaise]] and confusion, which can rapidly progress to stupor, [[coma]], and multi-organ failure. The characteristic rash, often seen early in the course of illness, resembles a sunburn, and can involve any region of the body, including the lips, mouth, eyes, palms and soles. In patients who survive the initial onslaught of the infection, the rash ''desquamates'', or peels off, after 10–14 days.


In contrast, TSLS is caused by the bacteria ''[[Streptococcus pyogenes]]'', and it typically presents in people with pre-existing skin infections with the bacteria. These individuals often experience severe pain at the site of the skin infection, followed by rapid progression of symptoms as described above for TSS. In contrast to TSS caused by Staphylococcus, Streptococcal TSS less often involves a sunburn-rash.
=== [[Staphylococcus|Staphylococcal]] [[TSS]] ===
Staphylococcal TSS can be devided into 2 major categories based on the disease cause: menstrual and nonmenstrual illness.<ref name="pmid2122225">{{cite journal |vauthors=Wharton M, Chorba TL, Vogt RL, Morse DL, Buehler JW |title=Case definitions for public health surveillance |journal=MMWR Recomm Rep |volume=39 |issue=RR-13 |pages=1–43 |year=1990 |pmid=2122225 |doi= |url=}}</ref>
 
Staphylococcal TSS also occurs in children. Patients younger than 2 years account for approximately half of the cases, and 62% have a history of preceding cutaneous nonsurgical lesions.10603216


==References==
==References==

Revision as of 11:32, 8 May 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Toxic shock syndrome (TSS) is characterized by sudden onset of fever, chills, vomiting, diarrhea, muscle aches and rash. It can rapidly progress to severe and intractable hypotension and multisystem dysfunction. Desquamation, particularly on the palms and soles can occur 1-2 weeks after onset of the illness.

History and Symptoms

Staphylococcal TSS

Staphylococcal TSS can be devided into 2 major categories based on the disease cause: menstrual and nonmenstrual illness.[1]

Staphylococcal TSS also occurs in children. Patients younger than 2 years account for approximately half of the cases, and 62% have a history of preceding cutaneous nonsurgical lesions.10603216

References

  1. Wharton M, Chorba TL, Vogt RL, Morse DL, Buehler JW (1990). "Case definitions for public health surveillance". MMWR Recomm Rep. 39 (RR-13): 1–43. PMID 2122225.


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