Toxic shock syndrome diagnostic criteria: Difference between revisions
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
The diagnosis is dependent upon which organism is responsible for the TSS: | |||
=== [[Staphylococcus|Staphylococcal]] [[Toxic shock syndrome|TSS]] === | |||
The diagnosis of toxic shock syndrome (TSS) is based upon clinical presentation as no confirmatory diagnostic criteria is developed yet. A criteria list have been established by United States Centers for Disease Control and Prevention ([[Centers for Disease Control and Prevention|CDC]]) for epidemiologic studies on Staphylococcal TSS, mean that a patient can not be excluded from disease based on the absence of one of these criterias when it come to diagnosis terms: | |||
* [[Fever]]: Temperature ≥38.9°C (102.0°F) | |||
# | * Serologic tests for [[Rocky Mountain spotted fever]], [[leptospirosis]], or [[measles]] | ||
# | * [[Hypotension]]: Systolic blood pressure ≤90 mmHg for adults or less than 5th percentile by age for children <16 years of age | ||
# | * [[Diffuse macular erythroderma]] | ||
* [[Desquamation]]: 1 to 2 weeks after onset of illness, particularly involving palms and soles | |||
# | * Multisystem involvement (3 or more of the following organ systems) | ||
# | # Gastrointestinal: Vomiting or diarrhea at onset of illness | ||
# Muscular: Severe [[myalgia]] or [[creatine phosphokinase]] elevation >2 times the upper limit of normal | |||
# Mucous membranes: Vaginal, oropharyngeal, or conjunctival [[hyperemia]] | |||
# Renal: [[Blood urea nitrogen]] or serum [[creatinine]] >2 times the upper limit of normal or [[pyuria]] (>5 white blood count/high power field) in the absence of urinary tract infection | |||
# Hepatic: [[Bilirubin]] or [[Transaminase|transaminases]] >2 times the upper limit of normal | |||
# Hematologic: Platelets <100,000/microL | |||
# [[Central nervous system]]: Disorientation or alterations in consciousness without focal neurologic signs in the absence of fever and hypotension | |||
# Negative results on the following tests, if obtained: Blood or [[cerebrospinal fluid]] cultures for another pathogen (blood cultures may be positive for Staphylococcus aureus) | |||
==References== | ==References== | ||
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Diagnostic Criteria
The diagnosis is dependent upon which organism is responsible for the TSS:
Staphylococcal TSS
The diagnosis of toxic shock syndrome (TSS) is based upon clinical presentation as no confirmatory diagnostic criteria is developed yet. A criteria list have been established by United States Centers for Disease Control and Prevention (CDC) for epidemiologic studies on Staphylococcal TSS, mean that a patient can not be excluded from disease based on the absence of one of these criterias when it come to diagnosis terms:
- Fever: Temperature ≥38.9°C (102.0°F)
- Serologic tests for Rocky Mountain spotted fever, leptospirosis, or measles
- Hypotension: Systolic blood pressure ≤90 mmHg for adults or less than 5th percentile by age for children <16 years of age
- Diffuse macular erythroderma
- Desquamation: 1 to 2 weeks after onset of illness, particularly involving palms and soles
- Multisystem involvement (3 or more of the following organ systems)
- Gastrointestinal: Vomiting or diarrhea at onset of illness
- Muscular: Severe myalgia or creatine phosphokinase elevation >2 times the upper limit of normal
- Mucous membranes: Vaginal, oropharyngeal, or conjunctival hyperemia
- Renal: Blood urea nitrogen or serum creatinine >2 times the upper limit of normal or pyuria (>5 white blood count/high power field) in the absence of urinary tract infection
- Hepatic: Bilirubin or transaminases >2 times the upper limit of normal
- Hematologic: Platelets <100,000/microL
- Central nervous system: Disorientation or alterations in consciousness without focal neurologic signs in the absence of fever and hypotension
- Negative results on the following tests, if obtained: Blood or cerebrospinal fluid cultures for another pathogen (blood cultures may be positive for Staphylococcus aureus)