Toloxatone: Difference between revisions
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{{ | {{Drugbox | ||
| IUPAC_name = 5-(hydroxymethyl)-3- | | Verifiedfields = changed | ||
| verifiedrevid = 470611624 | |||
| IUPAC_name = 5-(hydroxymethyl)-3-''m''-tolyloxazolidin-2-one | |||
| image = Toloxatone.png | | image = Toloxatone.png | ||
<!--Clinical data--> | <!--Clinical data--> | ||
| tradename = | | tradename = | ||
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__NOTOC__ | __NOTOC__ | ||
{{SI}} | {{SI}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
'''Toloxatone''' ('''Humoryl''') is an [[antidepressant]] launched in 1984 in France for the treatment of [[Major depressive disorder|depression]]. It acts as a selective [[reversible inhibitor of monoamine oxidase A|reversible inhibitor of MAO-A]] (RIMA).<ref name="pmid1705137">{{cite journal |author=Berlin I, Zimmer R, Thiede HM, ''et al.'' |title=Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects |journal=British Journal of Clinical Pharmacology |volume=30 |issue=6 |pages=805–16 |date=December 1990 |pmid=1705137 |pmc=1368300 |doi= 10.1111/j.1365-2125.1990.tb05445.x|url=}}</ref> | '''Toloxatone''' ('''Humoryl''') is an [[antidepressant]] launched in 1984 in France for the treatment of [[Major depressive disorder|depression]]. It acts as a selective [[reversible inhibitor of monoamine oxidase A|reversible inhibitor of MAO-A]] (RIMA).<ref name="pmid1705137">{{cite journal |author=Berlin I, Zimmer R, Thiede HM, ''et al.'' |title=Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects |journal=British Journal of Clinical Pharmacology |volume=30 |issue=6 |pages=805–16 |date=December 1990 |pmid=1705137 |pmc=1368300 |doi= 10.1111/j.1365-2125.1990.tb05445.x|url=}}</ref> | ||
Latest revision as of 17:18, 20 August 2015
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Routes of administration | Oral |
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E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C11H13NO3 |
Molar mass | 207.226 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Toloxatone (Humoryl) is an antidepressant launched in 1984 in France for the treatment of depression. It acts as a selective reversible inhibitor of MAO-A (RIMA).[1]
References
- ↑ Berlin I, Zimmer R, Thiede HM; et al. (December 1990). "Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects". British Journal of Clinical Pharmacology. 30 (6): 805–16. doi:10.1111/j.1365-2125.1990.tb05445.x. PMC 1368300. PMID 1705137.
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- Monoamine oxidase inhibitors
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