Thrombophilia screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Asiri Ediriwickrema, M.D., M.H.S. [2]

Screening

• The American Society of Hematology recommends against thrombophilia screening in adult patients with venous thrombosis in the setting of major transient risk factors.
  • Major transient risk factors including: surgery, trauma, or prolonged immobility.
  • However, patients who have significant risk factors including a positive family history or concurrent treatment with hormonal therapies should seek expert consultation.
• Thrombophilia screening can be expensive, and are often performed at inappropriate times.
• Refer to thrombophilia laboratory findings for more information on specific screening tests.