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Cutaneous cryptococcosis: | Cutaneous cryptococcosis: | ||
*Cryptococcus neoformans is an encapsulated yeast | |||
*Occurs in patients with advanced HIV (CD4<100/mm3) | *Occurs in patients with advanced HIV (CD4<100/mm3) | ||
*The most common manifestation is meningoencephalitis | *The most common manifestation is meningoencephalitis | ||
| Line 12: | Line 12: | ||
DD: | DD: | ||
*Kaposi Sarcoma: | |||
**Primarily presents in homosexual men(men with HIV who are sexually active with other men) | |||
**Red or purple papules with no necrosis | |||
*Basal cell carcinoma | *Basal cell carcinoma | ||
**Single, pink, flesh-colored papules | **Single, pink, flesh-colored papules | ||
**Arise slowly | **Arise slowly | ||
Revision as of 23:08, 14 October 2019
Cutaneous cryptococcosis:
- Cryptococcus neoformans is an encapsulated yeast
- Occurs in patients with advanced HIV (CD4<100/mm3)
- The most common manifestation is meningoencephalitis
- Pulmonary and/or disseminated disease may occur
- Cutaneous cryptococcosis considered as a marker of disseminated disease
- Rapid onset of multiple widespread papular lesions with central umbilication
- Diagnostic clue is the presence of a small area of central hemorrhage or necrosis
- Resembles molluscum contagiosum
- Most common areas affected are head and neck
- Disseminated infections can affect liver, lymph nodes, peritoneum, adrenal gland, and eyes
DD:
- Kaposi Sarcoma:
- Primarily presents in homosexual men(men with HIV who are sexually active with other men)
- Red or purple papules with no necrosis
- Basal cell carcinoma
- Single, pink, flesh-colored papules
- Arise slowly