Template:ID-Parasitic meningitis

• Protozoal meningitis

• Pathogen-directed antimicrobial therapy

• Naegleria fowleri (primary amebic meningoencephalitis)

• Preferred regimen: Amphotericin B 1.5 mg/kg/day IV q12h for 3 days, followed by Amphotericin B 1 mg/kg/day IV for 6 days AND Amphotericin B 1.5 mg/kg/day intrathecal for 2 days, followed by Amphotericin B 1 mg/kg/day intrathecal qod for 8 days
• Alternative regimen: Amphotericin B 0.25–1 mg/kg/day IV q24h for 2 weeks AND Fluconazole 10 mg/kg IV q24h for 30 days AND Rifampicin 10 mg/kg PO qd for 30 days AND Dexamethasone 0.15 mg/kg IV q6h for 30 days