TSPAN13: Difference between revisions

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{{Infobox_gene}}
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'''Tetraspanin-13''' is a [[protein]] that in humans is encoded by the ''TSPAN13'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TSPAN13 tetraspanin 13| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27075| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Tetraspanin 13
| HGNCid = 21643
| Symbol = TSPAN13
| AltSymbols =; FLJ22934; NET-6; TM4SF13
| OMIM = 
| ECnumber = 
| Homologene = 8671
| MGIid = 1913359
| GeneAtlas_image1 = PBB_GE_TSPAN13_217979_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 27075
    | Hs_Ensembl = ENSG00000106537
    | Hs_RefseqProtein = NP_055214
    | Hs_RefseqmRNA = NM_014399
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 16759853
    | Hs_GenLoc_end = 16790630
    | Hs_Uniprot = O95857
    | Mm_EntrezGene = 66109
    | Mm_Ensembl = ENSMUSG00000020577
    | Mm_RefseqmRNA = NM_025359
    | Mm_RefseqProtein = NP_079635
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 36524823
    | Mm_GenLoc_end = 36552755
    | Mm_Uniprot = Q9D8C2
  }}
}}
'''Tetraspanin 13''', also known as '''TSPAN13''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TSPAN13 tetraspanin 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27075| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.<ref name="entrez">{{cite web | title = Entrez Gene: TSPAN13 tetraspanin 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27075| accessdate = }}</ref>
| summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the [[tetraspanin]] family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Böhme E, Graf H, Schultz G |title=Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic GMP formation in smooth muscle and platelets. |journal=Advances in cyclic nucleotide research |volume=9 |issue=  |pages= 131-43 |year= 1978 |pmid= 27075 |doi=  }}
*{{cite journal  |vauthors=Böhme E, Graf H, Schultz G |title=Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic GMP formation in smooth muscle and platelets |journal=Advances in cyclic nucleotide research |volume=9 |issue=  |pages= 131–43 |year= 1978 |pmid= 27075 |doi=  }}
*{{cite journal  | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye. |journal=J. Cell. Sci. |volume=114 |issue= Pt 23 |pages= 4143-51 |year= 2002 |pmid= 11739647 |doi=  }}
*{{cite journal  | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye |journal=J. Cell Sci. |volume=114 |issue= Pt 23 |pages= 4143–51 |year= 2002 |pmid= 11739647 |doi=  }}
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
*{{cite journal  |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
*{{cite journal  | author=Serru V, Dessen P, Boucheix C, Rubinstein E |title=Sequence and expression of seven new tetraspans. |journal=Biochim. Biophys. Acta |volume=1478 |issue= 1 |pages= 159-63 |year= 2000 |pmid= 10719184 |doi=  }}
*{{cite journal  |vauthors=Serru V, Dessen P, Boucheix C, Rubinstein E |title=Sequence and expression of seven new tetraspans |journal=Biochim. Biophys. Acta |volume=1478 |issue= 1 |pages= 159–63 |year= 2000 |pmid= 10719184 |doi=10.1016/S0167-4838(00)00022-4 }}
*{{cite journal  | author=Hu RM, Han ZG, Song HD, ''et al.'' |title=Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9543-8 |year= 2000 |pmid= 10931946 |doi= 10.1073/pnas.160270997 }}
*{{cite journal  | author=Hu RM |title=Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9543–8 |year= 2000 |pmid= 10931946 |doi= 10.1073/pnas.160270997 | pmc=16901  |name-list-format=vanc| author2=Han ZG  | author3=Song HD  | display-authors=3  | last4=Peng  | first4=YD  | last5=Huang  | first5=QH  | last6=Ren  | first6=SX  | last7=Gu  | first7=YJ  | last8=Huang  | first8=CH  | last9=Li  | first9=YB }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Scherer SW |title=Human Chromosome 7: DNA Sequence and Biology |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 | pmc=2882961  |name-list-format=vanc| author2=Cheung J  | author3=MacDonald JR  | display-authors=3  | last4=Osborne  | first4=LR  | last5=Nakabayashi  | first5=K  | last6=Herbrick  | first6=JA  | last7=Carson  | first7=AR  | last8=Parker-Katiraee  | first8=L  | last9=Skaug  | first9=J }}
*{{cite journal  | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal  | author=Clark HF |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697  |name-list-format=vanc| author2=Gurney AL  | author3=Abaya E  | display-authors=3  | last4=Baker  | first4=K  | last5=Baldwin  | first5=D  | last6=Brush  | first6=J  | last7=Chen  | first7=J  | last8=Chow  | first8=B  | last9=Chui  | first9=C }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Huang H, Groth J, Sossey-Alaoui K, ''et al.'' |title=Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. |journal=Clin. Cancer Res. |volume=11 |issue= 12 |pages= 4357-64 |year= 2005 |pmid= 15958618 |doi= 10.1158/1078-0432.CCR-04-2107 }}
*{{cite journal  | author=Huang H |title=Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors |journal=Clin. Cancer Res. |volume=11 |issue= 12 |pages= 4357–64 |year= 2005 |pmid= 15958618 |doi= 10.1158/1078-0432.CCR-04-2107 |name-list-format=vanc| author2=Groth J  | author3=Sossey-Alaoui K  | display-authors=3  | last4=Hawthorn  | first4=L  | last5=Beall  | first5=S  | last6=Geradts  | first6=J }}
*{{cite journal  | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal  | author=Otsuki T |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 |name-list-format=vanc| author2=Ota T  | author3=Nishikawa T  | display-authors=3  | last4=Hayashi  | first4=K  | last5=Suzuki  | first5=Y  | last6=Yamamoto  | first6=J  | last7=Wakamatsu  | first7=A  | last8=Kimura  | first8=K  | last9=Sakamoto  | first9=K }}
*{{cite journal  | author=Moroz MA, Serganova I, Zanzonico P, ''et al.'' |title=Imaging hNET reporter gene expression with 124I-MIBG. |journal=J. Nucl. Med. |volume=48 |issue= 5 |pages= 827-36 |year= 2007 |pmid= 17475971 |doi= 10.2967/jnumed.106.037812 }}
*{{cite journal  | author=Moroz MA |title=Imaging hNET reporter gene expression with 124I-MIBG |journal=J. Nucl. Med. |volume=48 |issue= 5 |pages= 827–36 |year= 2007 |pmid= 17475971 |doi= 10.2967/jnumed.106.037812 |name-list-format=vanc| author2=Serganova I  | author3=Zanzonico P  | display-authors=3  | last4=Ageyeva  | first4=L.  | last5=Beresten  | first5=T.  | last6=Dyomina  | first6=E.  | last7=Burnazi  | first7=E.  | last8=Finn  | first8=R. D.  | last9=Doubrovin  | first9=M. }}
}}
}}
{{refend}}
{{refend}}
{{Membrane proteins}}
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Latest revision as of 21:03, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Tetraspanin-13 is a protein that in humans is encoded by the TSPAN13 gene.[1]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[1]

References

  1. ↑ 1.0 1.1 "Entrez Gene: TSPAN13 tetraspanin 13".

Further reading



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