TNPO2: Difference between revisions

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{{Infobox_gene}}
{{Infobox_gene}}
'''Transportin-2''' is a [[protein]] that in humans is encoded by the ''TNPO2'' [[gene]].<ref name="pmid9298975">{{cite journal |vauthors=Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G | title = Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins | journal = J Cell Biol | volume = 138 | issue = 6 | pages = 1181–92 |date=October 1997 | pmid = 9298975 | pmc = 2132560 | doi =10.1083/jcb.138.6.1181  }}</ref><ref name="pmid12384575">{{cite journal |vauthors=Shamsher MK, Ploski J, Radu A | title = Karyopherin beta 2B participates in mRNA export from the nucleus | journal = Proc Natl Acad Sci U S A | volume = 99 | issue = 22 | pages = 14195–9 |date=October 2002 | pmid = 12384575 | pmc = 137860 | doi = 10.1073/pnas.212518199 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30000| accessdate = }}</ref>
'''Transportin-2''' is a [[protein]] that in humans is encoded by the ''TNPO2'' [[gene]].<ref name="pmid9298975">{{cite journal |vauthors=Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G | title = Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins | journal = J Cell Biol | volume = 138 | issue = 6 | pages = 1181–92 |date=October 1997 | pmid = 9298975 | pmc = 2132560 | doi =10.1083/jcb.138.6.1181  }}</ref><ref name="pmid12384575">{{cite journal |vauthors=Shamsher MK, Ploski J, Radu A | title = Karyopherin beta 2B participates in mRNA export from the nucleus | journal = Proc Natl Acad Sci U S A | volume = 99 | issue = 22 | pages = 14195–9 |date=October 2002 | pmid = 12384575 | pmc = 137860 | doi = 10.1073/pnas.212518199 | bibcode = 2002PNAS...9914195S }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=30000| accessdate = }}</ref>


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{{PBB_Further_reading  
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| citations =  
| citations =  
*{{cite journal  |vauthors=Gallouzi IE, Steitz JA |title=Delineation of mRNA export pathways by the use of cell-permeable peptides. |journal=Science |volume=294 |issue= 5548 |pages= 1895–901 |year= 2001 |pmid= 11729309 |doi= 10.1126/science.1064693 }}
*{{cite journal  |vauthors=Gallouzi IE, Steitz JA |title=Delineation of mRNA export pathways by the use of cell-permeable peptides. |journal=Science |volume=294 |issue= 5548 |pages= 1895–901 |year= 2001 |pmid= 11729309 |doi= 10.1126/science.1064693 |bibcode=2001Sci...294.1895G }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal  |vauthors=Blanc V, Kennedy S, Davidson NO |title=A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling. |journal=J. Biol. Chem. |volume=278 |issue= 42 |pages= 41198–204 |year= 2003 |pmid= 12896982 |doi= 10.1074/jbc.M302951200 }}
*{{cite journal  |vauthors=Blanc V, Kennedy S, Davidson NO |title=A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling. |journal=J. Biol. Chem. |volume=278 |issue= 42 |pages= 41198–204 |year= 2003 |pmid= 12896982 |doi= 10.1074/jbc.M302951200 }}
*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Güttinger S, Mühlhäusser P, Koller-Eichhorn R, etal |title=Transportin2 functions as importin and mediates nuclear import of HuR. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 9 |pages= 2918–23 |year= 2004 |pmid= 14981248 |doi= 10.1073/pnas.0400342101  | pmc=365720 }}
*{{cite journal  |vauthors=Güttinger S, Mühlhäusser P, Koller-Eichhorn R, etal |title=Transportin2 functions as importin and mediates nuclear import of HuR. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 9 |pages= 2918–23 |year= 2004 |pmid= 14981248 |doi= 10.1073/pnas.0400342101  | pmc=365720 |bibcode=2004PNAS..101.2918G }}
*{{cite journal  |vauthors=Rebane A, Aab A, Steitz JA |title=Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. |journal=RNA |volume=10 |issue= 4 |pages= 590–9 |year= 2004 |pmid= 15037768 |doi=10.1261/rna.5224304  | pmc=1370549  }}
*{{cite journal  |vauthors=Rebane A, Aab A, Steitz JA |title=Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. |journal=RNA |volume=10 |issue= 4 |pages= 590–9 |year= 2004 |pmid= 15037768 |doi=10.1261/rna.5224304  | pmc=1370549  }}
*{{cite journal  |vauthors=Lee BJ, Cansizoglu AE, Süel KE, etal |title=Rules for nuclear localization sequence recognition by karyopherin beta 2. |journal=Cell |volume=126 |issue= 3 |pages= 543–58 |year= 2006 |pmid= 16901787 |doi= 10.1016/j.cell.2006.05.049 |pmc=3442361}}
*{{cite journal  |vauthors=Lee BJ, Cansizoglu AE, Süel KE, etal |title=Rules for nuclear localization sequence recognition by karyopherin beta 2. |journal=Cell |volume=126 |issue= 3 |pages= 543–58 |year= 2006 |pmid= 16901787 |doi= 10.1016/j.cell.2006.05.049 |pmc=3442361}}

Latest revision as of 19:14, 26 June 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.[1][2][3]


Interactions

TNPO2 has been shown to interact with NXF1,[2] NUP98[4] and Ran (biology).[2]

References

  1. Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (October 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". J Cell Biol. 138 (6): 1181–92. doi:10.1083/jcb.138.6.1181. PMC 2132560. PMID 9298975.
  2. 2.0 2.1 2.2 Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proc Natl Acad Sci U S A. 99 (22): 14195–9. Bibcode:2002PNAS...9914195S. doi:10.1073/pnas.212518199. PMC 137860. PMID 12384575.
  3. "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)".
  4. Fontoura, B M; Blobel G; Yaseen N R (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". J. Biol. Chem. UNITED STATES. 275 (40): 31289–96. doi:10.1074/jbc.M004651200. ISSN 0021-9258. PMID 10875935.

Further reading