T-cell prolymphocytic leukemia physical examination: Difference between revisions

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{{T-cell prolymphocytic leukemia}}                                                                 
{{CMG}}; {{AE}}{{Qurrat}}, {{MV}}


{{T-cell-prolymphocytic leukemia}}
{{CMG}}
==Overview==
==Overview==
On [[physical examination]], the [[patient]] appears pale due to [[anemia]]. [[Splenomegaly]] and [[hepatomegaly]] on [[abdominal examination]].
==Physical Examiantion==
==Physical Examiantion==
Due to the systemic nature of this disease, leukemic cells can be found in peripheral blood, [[lymph nodes]], [[bone marrow]], [[spleen]], [[liver]], [[skin]].
*Patients with T-cell prolymphocytic leukemia usually appear pale and [[malnourished]]. 
Patients typically have systemic disease at presentation, including [[hepatosplenomegaly]], generalized [[lymphadenopathy]], and skin infiltrates.
*[[Physical examination]] may be remarkable for:<ref name="pmid23382603">{{cite journal |vauthors=Graham RL, Cooper B, Krause JR |title=T-cell prolymphocytic leukemia |journal=Proc (Bayl Univ Med Cent) |volume=26 |issue=1 |pages=19–21 |year=2013 |pmid=23382603 |pmc=3523759 |doi= |url=}}</ref>
 
:*[[Hepatomegaly]]  
:*[[Splenomegaly]]
:*[[Generalized lymphadenopathy]]
:*Skin infiltration
:*[[Serous fluid|Serous]] [[Pleural Effusion|effusions]]:
:**[[Pleural effusion]]
:**[[Peritoneum|Peritoneal]] effusion
:*[[Central nervous system]] involvement (very rare)
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 13:14, 4 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Maria Fernanda Villarreal, M.D. [3]

Overview

On physical examination, the patient appears pale due to anemia. Splenomegaly and hepatomegaly on abdominal examination.

Physical Examiantion

References

  1. Graham RL, Cooper B, Krause JR (2013). "T-cell prolymphocytic leukemia". Proc (Bayl Univ Med Cent). 26 (1): 19–21. PMC 3523759. PMID 23382603.

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