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{{Systemic lupus erythematosus}}
{{Systemic lupus erythematosus}}
 
{{CMG}} ; {{AE}} {{MIR}}
{{CMG}}; {{AE}} {{RT}}


==Overview==
==Overview==
There is no established method for the primary prevention of systemic lupus erythematosus.


==Prevention==
==Primary Prevention==
 
There is no established method for prevention of systemic lupus erythematosus. However, preventing exposure to the [[Risk factor|risk factors]] listed below, especially flare-up-related [[risk factors]], can help to decrease flare-up episodes or may even be helpful in SLE prevention:
Lupus is not understood well enough to be prevented, but when the disease develops, quality of life can be improved through flare prevention. The warning signs of an impending flare include increased fatigue, pain, rash, fever, abdominal discomfort, headache and dizziness. Early recognition of warning signs and good communication with a doctor can help individuals with lupus remain active, experience less pain and reduce medical visits.
*Preventing exposure to [[ultraviolet]] (UV) light
 
*Cigarette smoking cessation<ref name="pmid11708417">{{cite journal |vauthors=Ghaussy NO, Sibbitt WL, Qualls CR |title=Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: a case-control study |journal=J. Rheumatol. |volume=28 |issue=11 |pages=2449–53 |year=2001 |pmid=11708417 |doi= |url=}}</ref>
===Prevention of complications during pregnancy===
*Prevent working in crystalline silica work environment (e.g., cleaning powders, soil, pottery materials, cement, etc.) <ref name="pmid12124868">{{cite journal |vauthors=Parks CG, Cooper GS, Nylander-French LA, Sanderson WT, Dement JM, Cohen PL, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS, Hoppin JA, Savitz DA |title=Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States |journal=Arthritis Rheum. |volume=46 |issue=7 |pages=1840–50 |year=2002 |pmid=12124868 |doi=10.1002/art.10368 |url=}}</ref>
*Prevent caring for a pet (especially a dog)


While most infants born to mothers who have SLE are healthy, pregnant mothers with SLE should remain under a doctor's care until delivery. Neonatal lupus is rare, but identification of mothers at highest risk for complications allows for prompt treatment before or after birth.  In addition, SLE can flare during pregnancy, and proper treatment can maintain the health of the mother longer. Women pregnant and known to have the antibodies for anti-Ro (SSA) or anti-La (SSB) should have echocardiograms during the 16th and 30th weeks of pregnancy to monitor the health of the heart and surrounding vasculature.<ref name=niams/>
=== Protection ===
 
Moderate alcohol drinking may be protective for SLE.<ref name="pmid18795396">{{cite journal |vauthors=Wang J, Pan HF, Ye DQ, Su H, Li XP |title=Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis |journal=Clin. Rheumatol. |volume=27 |issue=12 |pages=1557–63 |year=2008 |pmid=18795396 |doi=10.1007/s10067-008-1004-z |url=}}</ref>
Even [[contraception]] was routinely advised in treating SLE patients, getting pregnant during active disease was eventually found. [[Lupus nephritis]] was the most common manifestation. Overall live-birth was 72.7%. Pregnancy lost was due to [[abortion]] and dead fetus in utero. Pregnancy outcome was worse in SLE patients who had disease flares up or emerging during pregnancy.<ref name="pmid19253790">{{cite journal |author=Foocharoen C, Nanagara R, Salang L, Suwannaroj S, Mahakkanukrauh A |title=Pregnancy and disease outcome in patients with systemic lupus erythematosus (SLE): a study at Srinagarind Hospital |journal=J Med Assoc Thai |volume=92 |issue=2 |pages=167–74 |year=2009 |month=February |pmid=19253790 |doi= |url= |issn=}}</ref>


==References==
==References==
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{{Reflist|2}}
 
 
 
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[[Category:Arthritis]]
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[[Category:Nephrology]]
[[Category:Autoimmune diseases]]
[[Category:Disease]]

Latest revision as of 22:58, 22 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

There is no established method for the primary prevention of systemic lupus erythematosus.

Primary Prevention

There is no established method for prevention of systemic lupus erythematosus. However, preventing exposure to the risk factors listed below, especially flare-up-related risk factors, can help to decrease flare-up episodes or may even be helpful in SLE prevention:

  • Preventing exposure to ultraviolet (UV) light
  • Cigarette smoking cessation[1]
  • Prevent working in crystalline silica work environment (e.g., cleaning powders, soil, pottery materials, cement, etc.) [2]
  • Prevent caring for a pet (especially a dog)

Protection

Moderate alcohol drinking may be protective for SLE.[3]

References

  1. Ghaussy NO, Sibbitt WL, Qualls CR (2001). "Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: a case-control study". J. Rheumatol. 28 (11): 2449–53. PMID 11708417.
  2. Parks CG, Cooper GS, Nylander-French LA, Sanderson WT, Dement JM, Cohen PL, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS, Hoppin JA, Savitz DA (2002). "Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States". Arthritis Rheum. 46 (7): 1840–50. doi:10.1002/art.10368. PMID 12124868.
  3. Wang J, Pan HF, Ye DQ, Su H, Li XP (2008). "Moderate alcohol drinking might be protective for systemic lupus erythematosus: a systematic review and meta-analysis". Clin. Rheumatol. 27 (12): 1557–63. doi:10.1007/s10067-008-1004-z. PMID 18795396.

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