Syndrome of inappropriate antidiuretic hormone epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]

Overview

Syndrome of inappropriate antidiuretic hormone (SIADH) can occur at any age. Its incidence depends upon various possible etiologies. Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals. The incidence and prevalence of SIADH in particular is less thoroughly studied in the literature.

Epidemiology and Demographics

Prevalence

  • Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals.

Age

Gender

Race

  • There is no racial predilection to SIADH.

Mortality

  • Hospitalized patients with plasma sodium concentration <125 mmol/l show an overall mortality of 28000 per 100,000 patients.[3]

References

  1. Tarif N, Sabir O, Niaz A, Akhtar R, Rafique K, Rizvi N (2016). "Hyponatraemia: Epidemiology and aetiology in a tertiary care centre in Pakistan". J Pak Med Assoc. 66 (11): 1436–1439. PMID 27812063.
  2. Flear CT, Gill GV, Burn J (1981). "Hyponatraemia: mechanisms and management". Lancet. 2 (8236): 26–31. PMID 6113402.
  3. Gill, Geoffrey; Huda, Bobby; Boyd, Alice; Skagen, Karolina; Wile, David; Watson, Ian; van Heyningen, Charles (2006). "Characteristics and mortality of severe hyponatraemia ? a hospital-based study". Clinical Endocrinology. 65 (2): 246–249. doi:10.1111/j.1365-2265.2006.02583.x. ISSN 0300-0664.


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