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| {{drugbox
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| | IUPAC_name = N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl) -4-piperidyl]-N-phenyl-propanamide
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| | image = Sufentanil_Structure.png
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| | CAS_number = 56030-54-7
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| | ATC_prefix = N01
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| | ATC_suffix = AH03
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| | PubChem = 41693
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| | DrugBank = APRD00671
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| | C=22 | H=30 | N=2 | O=2 | S=1
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| | molecular_weight = 386.552 g/mol
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| | melting_point = 97
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| | bioavailability =
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| | protein_bound =
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| | metabolism =
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| | elimination_half-life = 265 minutes
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| | pregnancy_category =
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| | legal_status = Schedule II (USA)
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| | routes_of_administration = Injection
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| }}
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| '''Sufentanil''' is a synthetic [[opioid]] [[analgesic]] [[medication|drug]] approximately 5 to 10 times more potent than [[fentanyl]]. Sufentanil is marketed for use by specialist centres under different trade names, such as Sufenta and Sufentil ([[India]], by [[Claris Lifesciences]] Ltd.). Sufentanil was discovered at [[Janssen Pharmaceutica]].
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| ==Uses==
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| The main use of this medication is in operating suites and critical care where pain relief is required for a short period of time. It also offers properties of sedation and this makes it a good analgesic component of [[anaesthetic]] regimen during an operation. It is usually administered under the doctor's order through an [[intravenous]] route. In some countries sufentanil is only indicated for epidural use, despite this, it is often used off-label both intravenously and intranasally. A [[transdermal_patch|transdermal]] sufentanil patch called Transdur-sufentanil is currently in Stage I clinical trials by ENDO pharmaceuticals for the relief of chronic pain, and has the advantage over fentanyl patches such as [[Duragesic]] of only needing to be applied once per week.
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| ==Side effects==
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| It is essential for the administering doctor to be trained in [[airway management]] with readily available airway equipment because the drug causes significant [[respiratory depression]] and may cause [[respiratory arrest]] if given too much too rapidly. Other opioid side effects such as heart rhythm irregularity, blood pressure changes and nausea/vomiting can also be present in patients given this drug and should be dealt with accordingly by the doctor or anesthetist.
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| ==External links==
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| {{General anesthetics}}
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| [[de:Sufentanil]]
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| [[fr:Sufentanil]]
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| [[it:Sufentanil]]
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| [[sv:Sufentanil]]
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| [[th:ซูเฟนทานิล]]
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| [[Category:Analgesics]]
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| [[Category:Opioids]]
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| [[Category:Thiophenes]]
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| [[Category:Piperidines]]
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| [[Category:Drugs]]
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| [[pl:Sufentanyl]]
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