Spontaneous coronary artery dissection differential diagnosis

Spontaneous Coronary Artery Dissection Microchapters
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Overview
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Differentiating Spontaneous coronary artery dissection from other Diseases
Epidemiology and Demographics
Risk Factors
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Natural History, Complications and Prognosis
Diagnosis
Diagnostic Approach
History and Symptoms
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Medical Therapy
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Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Type 1 Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7 Type 2A Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Type 2B Case 1 Case 2 Case 3 Case 4 Type 3 Case 1 Case 2 Case 3 Case 4 Case 5 Case 6

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arzu Kalayci, M.D. [2]

Synonyms and keywords: SCAD

Differential Diagnosis

Albeit an infrequent condition, spontaneous coronary artery dissection (SCAD) should be included in the differential diagnosis of acute coronary syndrome (ACS). Demographic and angiographic characteristics may be useful in differentiating SCAD from other causes of ACS.

Demographic characteristics that favor the diagnosis of SCAD include:

• Myocardial infarction in young women (age ≤50)
• Absence of traditional cardiovascular risk factors
• Little or no evidence of coronary atherosclerosis
• Peripartum state
• History of fibromuscular dysplasia
• History of connective tissue disorder or systemic inflammatory disorder:

• Marfan's syndrome
• Type 4 Ehlers-Danlos syndrome
• Loeys-Dietz syndrome
• Cystic medial necrosis
• Systemic lupus erythematosus
• Crohn's disease
• Ulcerative colitis
• Polyarteritis nodosa
• Sarcoidosis
• Churg-Strauss syndrome
• Wegener's granulomatosis
• Rheumatoid arthritis
• Giant cell arteritis