Small nuclear ribonucleoprotein polypeptide F: Difference between revisions

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{{Infobox_gene}}
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'''Small nuclear ribonucleoprotein F''' is a [[protein]] that in humans is encoded by the ''SNRPF'' [[gene]].<ref name="pmid7744013">{{cite journal |vauthors=Hermann H, Fabrizio P, Raker VA, Foulaki K, Hornig H, Brahms H, Luhrmann R | title = snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions | journal = EMBO J | volume = 14 | issue = 9 | pages = 2076–88 |date=June 1995 | pmid = 7744013 | pmc = 398308 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNRPF small nuclear ribonucleoprotein polypeptide F| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6636| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Small nuclear ribonucleoprotein polypeptide F
| HGNCid = 11162
| Symbol = SNRPF
| AltSymbols =; SMF
| OMIM = 603541
| ECnumber = 
| Homologene = 2328
| MGIid = 1917128
| GeneAtlas_image1 = PBB_GE_SNRPF_203832_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005681 |text = spliceosome}} {{GNF_GO|id=GO:0030532 |text = small nuclear ribonucleoprotein complex}}
| Process = {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6636
    | Hs_Ensembl = ENSG00000139343
    | Hs_RefseqProtein = NP_003086
    | Hs_RefseqmRNA = NM_003095
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 94776847
    | Hs_GenLoc_end = 94784048
    | Hs_Uniprot = P62306
    | Mm_EntrezGene = 69878
    | Mm_Ensembl = ENSMUSG00000020018
    | Mm_RefseqmRNA = XM_892627
    | Mm_RefseqProtein = XP_897720
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 93013263
    | Mm_GenLoc_end = 93017922
    | Mm_Uniprot = Q3UX80
  }}
}}
'''Small nuclear ribonucleoprotein polypeptide F''', also known as '''SNRPF''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNRPF small nuclear ribonucleoprotein polypeptide F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6636| accessdate = }}</ref>


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==Interactions==
Small nuclear ribonucleoprotein polypeptide F has been shown to [[Protein-protein interaction|interact]] with [[DDX20]],<ref name=pmid10601333>{{cite journal |last=Charroux |first=B |authorlink= |author2=Pellizzoni L |author3=Perkinson R A |author4=Shevchenko A |author5=Mann M |author6=Dreyfuss G  |date=December 1999  |title=Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems |journal=J. Cell Biol. |volume=147 |issue=6 |pages=1181–94 |publisher= |location = UNITED STATES| issn = 0021-9525| pmid = 10601333 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1083/jcb.147.6.1181 |pmc=2168095 }}</ref> [[Small nuclear ribonucleoprotein D2]]<ref name=pmid9417867>{{cite journal |last=Fury |first=M G |authorlink= |author2=Zhang W |author3=Christodoulopoulos I |author4=Zieve G W  |date=November 1997  |title=Multiple protein: protein interactions between the snRNP common core proteins |journal=Exp. Cell Res. |volume=237 |issue=1 |pages=63–9 |publisher= |location = UNITED STATES| issn = 0014-4827| pmid = 9417867 |doi = 10.1006/excr.1997.3750 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[Small nuclear ribonucleoprotein polypeptide E]].<ref name=pmid9417867/>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Sauterer RA, Goyal A, Zieve GW |title=Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts. |journal=J. Biol. Chem. |volume=265 |issue= 2 |pages= 1048-58 |year= 1990 |pmid= 1688550 |doi=  }}
*{{cite journal  |vauthors=Sauterer RA, Goyal A, Zieve GW |title=Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts |journal=J. Biol. Chem. |volume=265 |issue= 2 |pages= 1048–58 |year= 1990 |pmid= 1688550 |doi=  }}
*{{cite journal  | author=Feeney RJ, Sauterer RA, Feeney JL, Zieve GW |title=Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles. |journal=J. Biol. Chem. |volume=264 |issue= 10 |pages= 5776-83 |year= 1989 |pmid= 2522439 |doi=  }}
*{{cite journal  |vauthors=Feeney RJ, Sauterer RA, Feeney JL, Zieve GW |title=Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles |journal=J. Biol. Chem. |volume=264 |issue= 10 |pages= 5776–83 |year= 1989 |pmid= 2522439 |doi=  }}
*{{cite journal  | author=Woppmann A, Rinke J, Lührmann R |title=Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ. |journal=Nucleic Acids Res. |volume=16 |issue= 23 |pages= 10985-1004 |year= 1989 |pmid= 2974540 |doi=  }}
*{{cite journal  |vauthors=Woppmann A, Rinke J, Lührmann R |title=Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ |journal=Nucleic Acids Res. |volume=16 |issue= 23 |pages= 10985–1004 |year= 1989 |pmid= 2974540 |doi=10.1093/nar/16.23.10985  | pmc=338992 }}
*{{cite journal  | author=Hermann H, Fabrizio P, Raker VA, ''et al.'' |title=snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. |journal=EMBO J. |volume=14 |issue= 9 |pages= 2076-88 |year= 1995 |pmid= 7744013 |doi=  }}
*{{cite journal  |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi= }}
*{{cite journal  |vauthors=Plessel G, Lührmann R, Kastner B |title=Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core |journal=J. Mol. Biol. |volume=265 |issue= 2 |pages= 87–94 |year= 1997 |pmid= 9020971 |doi= 10.1006/jmbi.1996.0713 }}
*{{cite journal  | author=Plessel G, Lührmann R, Kastner B |title=Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core. |journal=J. Mol. Biol. |volume=265 |issue= 2 |pages= 87-94 |year= 1997 |pmid= 9020971 |doi= 10.1006/jmbi.1996.0713 }}
*{{cite journal  |vauthors=Fury MG, Zhang W, Christodoulopoulos I, Zieve GW |title=Multiple protein: protein interactions between the snRNP common core proteins |journal=Exp. Cell Res. |volume=237 |issue= 1 |pages= 63–9 |year= 1998 |pmid= 9417867 |doi= 10.1006/excr.1997.3750 }}
*{{cite journal | author=Fury MG, Zhang W, Christodoulopoulos I, Zieve GW |title=Multiple protein: protein interactions between the snRNP common core proteins. |journal=Exp. Cell Res. |volume=237 |issue= 1 |pages= 63-9 |year= 1998 |pmid= 9417867 |doi= 10.1006/excr.1997.3750 }}
*{{cite journal   |vauthors=Kambach C, Walke S, Young R, etal |title=Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs |journal=Cell |volume=96 |issue= 3 |pages= 375–87 |year= 1999 |pmid= 10025403 |doi=10.1016/S0092-8674(00)80550-4  }}
*{{cite journal  | author=Kambach C, Walke S, Young R, ''et al.'' |title=Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. |journal=Cell |volume=96 |issue= 3 |pages= 375-87 |year= 1999 |pmid= 10025403 |doi=  }}
*{{cite journal  |vauthors=Bühler D, Raker V, Lührmann R, Fischer U |title=Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy |journal=Hum. Mol. Genet. |volume=8 |issue= 13 |pages= 2351–7 |year= 2000 |pmid= 10556282 |doi=10.1093/hmg/8.13.2351 }}
*{{cite journal | author=Bühler D, Raker V, Lührmann R, Fischer U |title=Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. |journal=Hum. Mol. Genet. |volume=8 |issue= 13 |pages= 2351-7 |year= 2000 |pmid= 10556282 |doi=  }}
*{{cite journal   |vauthors=Charroux B, Pellizzoni L, Perkinson RA, etal |title=Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems |journal=J. Cell Biol. |volume=147 |issue= 6 |pages= 1181–94 |year= 2000 |pmid= 10601333 |doi=10.1083/jcb.147.6.1181  | pmc=2168095 }}
*{{cite journal | author=Charroux B, Pellizzoni L, Perkinson RA, ''et al.'' |title=Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. |journal=J. Cell Biol. |volume=147 |issue= 6 |pages= 1181-94 |year= 2000 |pmid= 10601333 |doi= }}
*{{cite journal   |vauthors=Charroux B, Pellizzoni L, Perkinson RA, etal |title=Gemin4: A Novel Component of the Smn Complex That Is Found in Both Gems and Nucleoli |journal=J. Cell Biol. |volume=148 |issue= 6 |pages= 1177–86 |year= 2000 |pmid= 10725331 |doi=10.1083/jcb.148.6.1177  | pmc=2174312  }}
*{{cite journal  | author=Charroux B, Pellizzoni L, Perkinson RA, ''et al.'' |title=Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. |journal=J. Cell Biol. |volume=148 |issue= 6 |pages= 1177-86 |year= 2000 |pmid= 10725331 |doi=  }}
*{{cite journal  |vauthors=Urlaub H, Raker VA, Kostka S, Lührmann R |title=Sm protein–Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure |journal=EMBO J. |volume=20 |issue= 1–2 |pages= 187–96 |year= 2001 |pmid= 11226169 |doi= 10.1093/emboj/20.1.187 | pmc=140196 }}
*{{cite journal | author=Urlaub H, Raker VA, Kostka S, Lührmann R |title=Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. |journal=EMBO J. |volume=20 |issue= 1-2 |pages= 187-96 |year= 2001 |pmid= 11226169 |doi= 10.1093/emboj/20.1.187 }}
*{{cite journal   |vauthors=Pellizzoni L, Baccon J, Rappsilber J, etal |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540–5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200 }}
*{{cite journal | author=Pellizzoni L, Baccon J, Rappsilber J, ''et al.'' |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540-5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200 }}
*{{cite journal   |vauthors=Friesen WJ, Wyce A, Paushkin S, etal |title=A novel WD repeat protein component of the methylosome binds Sm proteins |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8243–7 |year= 2002 |pmid= 11756452 |doi= 10.1074/jbc.M109984200 }}
*{{cite journal | author=Friesen WJ, Wyce A, Paushkin S, ''et al.'' |title=A novel WD repeat protein component of the methylosome binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8243-7 |year= 2002 |pmid= 11756452 |doi= 10.1074/jbc.M109984200 }}
*{{cite journal   |vauthors=Jurica MS, Licklider LJ, Gygi SR, etal |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=10.1017/S1355838202021088  | pmc=1370266  }}
*{{cite journal | author=Jurica MS, Licklider LJ, Gygi SR, ''et al.'' |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426-39 |year= 2002 |pmid= 11991638 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Will CL, Schneider C, Hossbach M, etal |title=The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome |journal=RNA |volume=10 |issue= 6 |pages= 929–41 |year= 2004 |pmid= 15146077 |doi=10.1261/rna.7320604  | pmc=1370585  }}
*{{cite journal  | author=Will CL, Schneider C, Hossbach M, ''et al.'' |title=The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. |journal=RNA |volume=10 |issue= 6 |pages= 929-41 |year= 2004 |pmid= 15146077 |doi=  }}
*{{cite journal  |vauthors=Lehner B, Sanderson CM |title=A Protein Interaction Framework for Human mRNA Degradation |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}
*{{cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315-23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Ma Y, Dostie J, Dreyfuss G, Van Duyne GD |title=The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure |journal=Structure |volume=13 |issue= 6 |pages= 883–92 |year= 2005 |pmid= 15939020 |doi= 10.1016/j.str.2005.03.014 }}
*{{cite journal  | author=Ma Y, Dostie J, Dreyfuss G, Van Duyne GD |title=The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure. |journal=Structure |volume=13 |issue= 6 |pages= 883-92 |year= 2005 |pmid= 15939020 |doi= 10.1016/j.str.2005.03.014 }}
}}
}}
{{refend}}
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{{protein-stub}}
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{{Ribonucleoproteins}}
 
 
{{gene-12-stub}}

Revision as of 00:03, 12 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Small nuclear ribonucleoprotein F is a protein that in humans is encoded by the SNRPF gene.[1][2]


Interactions

Small nuclear ribonucleoprotein polypeptide F has been shown to interact with DDX20,[3] Small nuclear ribonucleoprotein D2[4] and Small nuclear ribonucleoprotein polypeptide E.[4]

References

  1. Hermann H, Fabrizio P, Raker VA, Foulaki K, Hornig H, Brahms H, Luhrmann R (June 1995). "snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions". EMBO J. 14 (9): 2076–88. PMC 398308. PMID 7744013.
  2. "Entrez Gene: SNRPF small nuclear ribonucleoprotein polypeptide F".
  3. Charroux, B; Pellizzoni L; Perkinson R A; Shevchenko A; Mann M; Dreyfuss G (December 1999). "Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems". J. Cell Biol. UNITED STATES. 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. ISSN 0021-9525. PMC 2168095. PMID 10601333.
  4. 4.0 4.1 Fury, M G; Zhang W; Christodoulopoulos I; Zieve G W (November 1997). "Multiple protein: protein interactions between the snRNP common core proteins". Exp. Cell Res. UNITED STATES. 237 (1): 63–9. doi:10.1006/excr.1997.3750. ISSN 0014-4827. PMID 9417867.

Further reading