Small nuclear ribonucleoprotein polypeptide E: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Small nuclear ribonucleoprotein E''' is a [[protein]] that in humans is encoded by the ''SNRPE'' [[gene]].<ref name="pmid1835977">{{cite journal | vauthors = Fautsch MP, Wieben ED | title = Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins | journal = The Journal of Biological Chemistry | volume = 266 | issue = 34 | pages = 23288–95 | date = December 1991 | pmid = 1835977 | pmc =  | doi =  }}</ref><ref name="pmid2143747">{{cite journal | vauthors = Neiswanger K, Stanford DR, Sparkes RS, Nishimura D, Mohandas T, Klisak I, Heinzmann C, Wieben ED | title = Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43 | journal = Genomics | volume = 7 | issue = 4 | pages = 503–8 | date = August 1990 | pmid = 2143747 | pmc =  | doi = 10.1016/0888-7543(90)90192-W }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNRPE small nuclear ribonucleoprotein polypeptide E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6635| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Small nuclear ribonucleoprotein polypeptide E
| HGNCid = 11161
| Symbol = SNRPE
| AltSymbols =; B-raf; SME
| OMIM = 128260
| ECnumber = 
| Homologene = 37729
| MGIid = 98346
| GeneAtlas_image1 = PBB_GE_SNRPE_203316_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005681 |text = spliceosome}} {{GNF_GO|id=GO:0030532 |text = small nuclear ribonucleoprotein complex}}
| Process = {{GNF_GO|id=GO:0000245 |text = spliceosome assembly}} {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6635
    | Hs_Ensembl = ENSG00000182004
    | Hs_RefseqProtein = NP_003085
    | Hs_RefseqmRNA = NM_003094
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 202097366
    | Hs_GenLoc_end = 202106301
    | Hs_Uniprot = P62304
    | Mm_EntrezGene = 20643
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = NM_009227
    | Mm_RefseqProtein = NP_033253
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Small nuclear ribonucleoprotein polypeptide E''', also known as '''SNRPE''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNRPE small nuclear ribonucleoprotein polypeptide E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6635| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
Small nuclear ribonucleoprotein polypeptide E has been shown to [[Protein-protein interaction|interact]] with [[DDX20]]<ref name=pmid10601333>{{cite journal | vauthors = Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G | title = Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems | journal = The Journal of Cell Biology | volume = 147 | issue = 6 | pages = 1181–94 | date = December 1999 | pmid = 10601333 | pmc = 2168095 | doi = 10.1083/jcb.147.6.1181 }}</ref> and [[Small nuclear ribonucleoprotein polypeptide F]].<ref name=pmid9417867>{{cite journal | vauthors = Fury MG, Zhang W, Christodoulopoulos I, Zieve GW | title = Multiple protein: protein interactions between the snRNP common core proteins | journal = Experimental Cell Research | volume = 237 | issue = 1 | pages = 63–9 | date = November 1997 | pmid = 9417867 | doi = 10.1006/excr.1997.3750 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Sauterer RA, Goyal A, Zieve GW | title = Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts | journal = The Journal of Biological Chemistry | volume = 265 | issue = 2 | pages = 1048–58 | date = January 1990 | pmid = 1688550 | doi =  }}
| citations =
* {{cite journal | vauthors = Stanford DR, Rohleder A, Neiswanger K, Wieben ED | title = DNA sequence of a human Sm autoimmune antigen. The multigene family contains a processed pseudogene | journal = The Journal of Biological Chemistry | volume = 262 | issue = 21 | pages = 9931–4 | date = July 1987 | pmid = 2440864 | doi =  }}
*{{cite journal | author=Sauterer RA, Goyal A, Zieve GW |title=Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts. |journal=J. Biol. Chem. |volume=265 |issue= 2 |pages= 1048-58 |year= 1990 |pmid= 1688550 |doi=  }}
* {{cite journal | vauthors = Feeney RJ, Sauterer RA, Feeney JL, Zieve GW | title = Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles | journal = The Journal of Biological Chemistry | volume = 264 | issue = 10 | pages = 5776–83 | date = April 1989 | pmid = 2522439 | doi =  }}
*{{cite journal | author=Fautsch MP, Wieben ED |title=Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins. |journal=J. Biol. Chem. |volume=266 |issue= 34 |pages= 23288-95 |year= 1992 |pmid= 1835977 |doi=  }}
* {{cite journal | vauthors = Stanford DR, Perry CA, Holicky EL, Rohleder AM, Wieben ED | title = The small nuclear ribonucleoprotein E protein gene contains four introns and has upstream similarities to genes for ribosomal proteins | journal = The Journal of Biological Chemistry | volume = 263 | issue = 33 | pages = 17772–9 | date = November 1988 | pmid = 2972723 | doi =  }}
*{{cite journal | author=Neiswanger K, Stanford DR, Sparkes RS, ''et al.'' |title=Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43. |journal=Genomics |volume=7 |issue= 4 |pages= 503-8 |year= 1990 |pmid= 2143747 |doi=  }}
* {{cite journal | vauthors = Stanford DR, Kehl M, Perry CA, Holicky EL, Harvey SE, Rohleder AM, Rehder K, Luhrmann R, Wieben ED | title = The complete primary structure of the human snRNP E protein | journal = Nucleic Acids Research | volume = 16 | issue = 22 | pages = 10593–605 | date = November 1988 | pmid = 2974536 | pmc = 338926 | doi = 10.1093/nar/16.22.10593 }}
*{{cite journal | author=Stanford DR, Rohleder A, Neiswanger K, Wieben ED |title=DNA sequence of a human Sm autoimmune antigen. The multigene family contains a processed pseudogene. |journal=J. Biol. Chem. |volume=262 |issue= 21 |pages= 9931-4 |year= 1987 |pmid= 2440864 |doi=  }}
* {{cite journal | vauthors = Woppmann A, Rinke J, Lührmann R | title = Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ | journal = Nucleic Acids Research | volume = 16 | issue = 23 | pages = 10985–1004 | date = December 1988 | pmid = 2974540 | pmc = 338992 | doi = 10.1093/nar/16.23.10985 }}
*{{cite journal | author=Feeney RJ, Sauterer RA, Feeney JL, Zieve GW |title=Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles. |journal=J. Biol. Chem. |volume=264 |issue= 10 |pages= 5776-83 |year= 1989 |pmid= 2522439 |doi= }}
* {{cite journal | vauthors = Kamiyama T, Aoki N, Yuasa Y | title = B-raf oncogene: activation by rearrangements and assignment to human chromosome 7 | journal = Japanese Journal of Cancer Research | volume = 84 | issue = 3 | pages = 250–6 | date = March 1993 | pmid = 8098025 | doi = 10.1111/j.1349-7006.1993.tb02864.x }}
*{{cite journal | author=Stanford DR, Perry CA, Holicky EL, ''et al.'' |title=The small nuclear ribonucleoprotein E protein gene contains four introns and has upstream similarities to genes for ribosomal proteins. |journal=J. Biol. Chem. |volume=263 |issue= 33 |pages= 17772-9 |year= 1988 |pmid= 2972723 |doi= }}
* {{cite journal | vauthors = Plessel G, Lührmann R, Kastner B | title = Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core | journal = Journal of Molecular Biology | volume = 265 | issue = 2 | pages = 87–94 | date = January 1997 | pmid = 9020971 | doi = 10.1006/jmbi.1996.0713 }}
*{{cite journal | author=Stanford DR, Kehl M, Perry CA, ''et al.'' |title=The complete primary structure of the human snRNP E protein. |journal=Nucleic Acids Res. |volume=16 |issue= 22 |pages= 10593-605 |year= 1989 |pmid= 2974536 |doi= }}
* {{cite journal | vauthors = Liu Q, Fischer U, Wang F, Dreyfuss G | title = The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins | journal = Cell | volume = 90 | issue = 6 | pages = 1013–21 | date = September 1997 | pmid = 9323129 | doi = 10.1016/S0092-8674(00)80367-0 }}
*{{cite journal | author=Woppmann A, Rinke J, Lührmann R |title=Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ. |journal=Nucleic Acids Res. |volume=16 |issue= 23 |pages= 10985-1004 |year= 1989 |pmid= 2974540 |doi= }}
* {{cite journal | vauthors = Fury MG, Zhang W, Christodoulopoulos I, Zieve GW | title = Multiple protein: protein interactions between the snRNP common core proteins | journal = Experimental Cell Research | volume = 237 | issue = 1 | pages = 63–9 | date = November 1997 | pmid = 9417867 | doi = 10.1006/excr.1997.3750 }}
*{{cite journal | author=Kamiyama T, Aoki N, Yuasa Y |title=B-raf oncogene: activation by rearrangements and assignment to human chromosome 7. |journal=Jpn. J. Cancer Res. |volume=84 |issue= 3 |pages= 250-6 |year= 1993 |pmid= 8098025 |doi= }}
* {{cite journal | vauthors = Kambach C, Walke S, Young R, Avis JM, de la Fortelle E, Raker VA, Lührmann R, Li J, Nagai K | title = Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs | journal = Cell | volume = 96 | issue = 3 | pages = 375–87 | date = February 1999 | pmid = 10025403 | doi = 10.1016/S0092-8674(00)80550-4 }}
*{{cite journal | author=Plessel G, Lührmann R, Kastner B |title=Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core. |journal=J. Mol. Biol. |volume=265 |issue= 2 |pages= 87-94 |year= 1997 |pmid= 9020971 |doi= 10.1006/jmbi.1996.0713 }}
* {{cite journal | vauthors = Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G | title = Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems | journal = The Journal of Cell Biology | volume = 147 | issue = 6 | pages = 1181–94 | date = December 1999 | pmid = 10601333 | pmc = 2168095 | doi = 10.1083/jcb.147.6.1181 }}
*{{cite journal | author=Liu Q, Fischer U, Wang F, Dreyfuss G |title=The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. |journal=Cell |volume=90 |issue= 6 |pages= 1013-21 |year= 1997 |pmid= 9323129 |doi= }}
* {{cite journal | vauthors = Charroux B, Pellizzoni L, Perkinson RA, Yong J, Shevchenko A, Mann M, Dreyfuss G | title = Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli | journal = The Journal of Cell Biology | volume = 148 | issue = 6 | pages = 1177–86 | date = March 2000 | pmid = 10725331 | pmc = 2174312 | doi = 10.1083/jcb.148.6.1177 }}
*{{cite journal | author=Fury MG, Zhang W, Christodoulopoulos I, Zieve GW |title=Multiple protein: protein interactions between the snRNP common core proteins. |journal=Exp. Cell Res. |volume=237 |issue= 1 |pages= 63-9 |year= 1998 |pmid= 9417867 |doi= 10.1006/excr.1997.3750 }}
* {{cite journal | vauthors = Urlaub H, Raker VA, Kostka S, Lührmann R | title = Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure | journal = The EMBO Journal | volume = 20 | issue = 1-2 | pages = 187–96 | date = January 2001 | pmid = 11226169 | pmc = 140196 | doi = 10.1093/emboj/20.1.187 }}
*{{cite journal | author=Kambach C, Walke S, Young R, ''et al.'' |title=Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. |journal=Cell |volume=96 |issue= 3 |pages= 375-87 |year= 1999 |pmid= 10025403 |doi= }}
* {{cite journal | vauthors = Gubitz AK, Mourelatos Z, Abel L, Rappsilber J, Mann M, Dreyfuss G | title = Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins | journal = The Journal of Biological Chemistry | volume = 277 | issue = 7 | pages = 5631–6 | date = February 2002 | pmid = 11714716 | doi = 10.1074/jbc.M109448200 }}
*{{cite journal | author=Charroux B, Pellizzoni L, Perkinson RA, ''et al.'' |title=Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. |journal=J. Cell Biol. |volume=147 |issue= 6 |pages= 1181-94 |year= 2000 |pmid= 10601333 |doi= }}
* {{cite journal | vauthors = Pellizzoni L, Baccon J, Rappsilber J, Mann M, Dreyfuss G | title = Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component | journal = The Journal of Biological Chemistry | volume = 277 | issue = 9 | pages = 7540–5 | date = March 2002 | pmid = 11748230 | doi = 10.1074/jbc.M110141200 }}
*{{cite journal | author=Charroux B, Pellizzoni L, Perkinson RA, ''et al.'' |title=Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. |journal=J. Cell Biol. |volume=148 |issue= 6 |pages= 1177-86 |year= 2000 |pmid= 10725331 |doi= }}
* {{cite journal | vauthors = Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G | title = A novel WD repeat protein component of the methylosome binds Sm proteins | journal = The Journal of Biological Chemistry | volume = 277 | issue = 10 | pages = 8243–7 | date = March 2002 | pmid = 11756452 | doi = 10.1074/jbc.M109984200 }}
*{{cite journal | author=Urlaub H, Raker VA, Kostka S, Lührmann R |title=Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. |journal=EMBO J. |volume=20 |issue= 1-2 |pages= 187-96 |year= 2001 |pmid= 11226169 |doi= 10.1093/emboj/20.1.187 }}
* {{cite journal | vauthors = Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ | title = Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | journal = RNA | volume = 8 | issue = 4 | pages = 426–39 | date = April 2002 | pmid = 11991638 | pmc = 1370266 | doi = 10.1017/S1355838202021088 }}
*{{cite journal | author=Gubitz AK, Mourelatos Z, Abel L, ''et al.'' |title=Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5631-6 |year= 2002 |pmid= 11714716 |doi= 10.1074/jbc.M109448200 }}
*{{cite journal | author=Pellizzoni L, Baccon J, Rappsilber J, ''et al.'' |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540-5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200 }}
*{{cite journal  | author=Friesen WJ, Wyce A, Paushkin S, ''et al.'' |title=A novel WD repeat protein component of the methylosome binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8243-7 |year= 2002 |pmid= 11756452 |doi= 10.1074/jbc.M109984200 }}
*{{cite journal  | author=Jurica MS, Licklider LJ, Gygi SR, ''et al.'' |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426-39 |year= 2002 |pmid= 11991638 |doi=  }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{Ribonucleoproteins}}
{{WikiDoc Sources}}
 
 
{{gene-1-stub}}

Latest revision as of 01:20, 28 November 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Small nuclear ribonucleoprotein E is a protein that in humans is encoded by the SNRPE gene.[1][2][3]

Interactions

Small nuclear ribonucleoprotein polypeptide E has been shown to interact with DDX20[4] and Small nuclear ribonucleoprotein polypeptide F.[5]

References

  1. Fautsch MP, Wieben ED (December 1991). "Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins". The Journal of Biological Chemistry. 266 (34): 23288–95. PMID 1835977.
  2. Neiswanger K, Stanford DR, Sparkes RS, Nishimura D, Mohandas T, Klisak I, Heinzmann C, Wieben ED (August 1990). "Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43". Genomics. 7 (4): 503–8. doi:10.1016/0888-7543(90)90192-W. PMID 2143747.
  3. "Entrez Gene: SNRPE small nuclear ribonucleoprotein polypeptide E".
  4. Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A, Mann M, Dreyfuss G (December 1999). "Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems". The Journal of Cell Biology. 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. PMC 2168095. PMID 10601333.
  5. Fury MG, Zhang W, Christodoulopoulos I, Zieve GW (November 1997). "Multiple protein: protein interactions between the snRNP common core proteins". Experimental Cell Research. 237 (1): 63–9. doi:10.1006/excr.1997.3750. PMID 9417867.

Further reading