Sexcord/ stromal ovarian tumors surgery: Difference between revisions

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==Surgery==
==Surgery==
*Surgery is the mainstay of treatment for sexcord/ stromal ovarian tumors<ref name="pmid24753008">{{cite journal |vauthors=Gurumurthy M, Bryant A, Shanbhag S |title=Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent) |journal=Cochrane Database Syst Rev |volume= |issue=4 |pages=CD006912 |date=April 2014 |pmid=24753008 |doi=10.1002/14651858.CD006912.pub2 |url=}}</ref><ref name="pmid24315353">{{cite journal |vauthors=Gremeau AS, Bourdel N, Jardon K, Rabischong B, Mage G, Pouly JL, Canis M |title=Surgical management of non-epithelial ovarian malignancies: advantages and limitations of laparoscopy |journal=Eur. J. Obstet. Gynecol. Reprod. Biol. |volume=172 |issue= |pages=106–10 |date=January 2014 |pmid=24315353 |doi=10.1016/j.ejogrb.2013.10.023 |url=}}</ref><ref name="pmid22525408">{{cite journal |vauthors=Schultz KA, Schneider DT, Pashankar F, Ross J, Frazier L |title=Management of ovarian and testicular sex cord-stromal tumors in children and adolescents |journal=J. Pediatr. Hematol. Oncol. |volume=34 Suppl 2 |issue= |pages=S55–63 |date=May 2012 |pmid=22525408 |doi=10.1097/MPH.0b013e31824e3867 |url=}}</ref><ref name="pmid22426486">{{cite journal |vauthors=Gershenson DM |title=Current advances in the management of malignant germ cell and sex cord-stromal tumors of the ovary |journal=Gynecol. Oncol. |volume=125 |issue=3 |pages=515–7 |date=June 2012 |pmid=22426486 |doi=10.1016/j.ygyno.2012.03.019 |url=}}</ref><ref name="pmid28276867">{{cite journal |vauthors=Färkkilä A, Haltia UM, Tapper J, McConechy MK, Huntsman DG, Heikinheimo M |title=Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary |journal=Ann. Med. |volume=49 |issue=5 |pages=435–447 |date=August 2017 |pmid=28276867 |doi=10.1080/07853890.2017.1294760 |url=}}</ref><ref name="pmid26411956">{{cite journal |vauthors=Uma Devi K, Purushotham N, Jayashree N |title=Management of Ovarian Cancer In Younger Women |journal=Rev Recent Clin Trials |volume=10 |issue=4 |pages=263–9 |date=2015 |pmid=26411956 |doi= |url=}}</ref><ref name="pmid25886261">{{cite journal |vauthors=Qian Q, You Y, Yang J, Cao D, Zhu Z, Wu M, Chen J, Lang J, Shen K |title=Management and prognosis of patients with ovarian sex cord tumor with annular tubules: a retrospective study |journal=BMC Cancer |volume=15 |issue= |pages=270 |date=April 2015 |pmid=25886261 |pmc=4408581 |doi=10.1186/s12885-015-1277-y |url=}}</ref>
*Surgery is the mainstay of treatment for sexcord/ stromal ovarian tumors<ref name="pmid24753008">{{cite journal |vauthors=Gurumurthy M, Bryant A, Shanbhag S |title=Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent) |journal=Cochrane Database Syst Rev |volume= |issue=4 |pages=CD006912 |date=April 2014 |pmid=24753008 |doi=10.1002/14651858.CD006912.pub2 |url=}}</ref><ref name="pmid24315353">{{cite journal |vauthors=Gremeau AS, Bourdel N, Jardon K, Rabischong B, Mage G, Pouly JL, Canis M |title=Surgical management of non-epithelial ovarian malignancies: advantages and limitations of laparoscopy |journal=Eur. J. Obstet. Gynecol. Reprod. Biol. |volume=172 |issue= |pages=106–10 |date=January 2014 |pmid=24315353 |doi=10.1016/j.ejogrb.2013.10.023 |url=}}</ref><ref name="pmid22525408">{{cite journal |vauthors=Schultz KA, Schneider DT, Pashankar F, Ross J, Frazier L |title=Management of ovarian and testicular sex cord-stromal tumors in children and adolescents |journal=J. Pediatr. Hematol. Oncol. |volume=34 Suppl 2 |issue= |pages=S55–63 |date=May 2012 |pmid=22525408 |doi=10.1097/MPH.0b013e31824e3867 |url=}}</ref><ref name="pmid22426486">{{cite journal |vauthors=Gershenson DM |title=Current advances in the management of malignant germ cell and sex cord-stromal tumors of the ovary |journal=Gynecol. Oncol. |volume=125 |issue=3 |pages=515–7 |date=June 2012 |pmid=22426486 |doi=10.1016/j.ygyno.2012.03.019 |url=}}</ref><ref name="pmid28276867">{{cite journal |vauthors=Färkkilä A, Haltia UM, Tapper J, McConechy MK, Huntsman DG, Heikinheimo M |title=Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary |journal=Ann. Med. |volume=49 |issue=5 |pages=435–447 |date=August 2017 |pmid=28276867 |doi=10.1080/07853890.2017.1294760 |url=}}</ref><ref name="pmid26411956">{{cite journal |vauthors=Uma Devi K, Purushotham N, Jayashree N |title=Management of Ovarian Cancer In Younger Women |journal=Rev Recent Clin Trials |volume=10 |issue=4 |pages=263–9 |date=2015 |pmid=26411956 |doi= |url=}}</ref><ref name="pmid25886261">{{cite journal |vauthors=Qian Q, You Y, Yang J, Cao D, Zhu Z, Wu M, Chen J, Lang J, Shen K |title=Management and prognosis of patients with ovarian sex cord tumor with annular tubules: a retrospective study |journal=BMC Cancer |volume=15 |issue= |pages=270 |date=April 2015 |pmid=25886261 |pmc=4408581 |doi=10.1186/s12885-015-1277-y |url=}}</ref><ref name="pmid25969483">{{cite journal |vauthors=Chatziioannidou K, Botsikas D, Tille JC, Dubuisson J |title=Preservation of fertility in non-Peutz-Jegher syndrome-associated ovarian sex cord tumour with annular tubules |journal=BMJ Case Rep |volume=2015 |issue= |pages= |date=May 2015 |pmid=25969483 |pmc=4434316 |doi=10.1136/bcr-2014-207841 |url=}}</ref>
*Both benign and malignant ovarian sex cord-stromal tumors are managed surgically
*Both benign and malignant ovarian sex cord-stromal tumors are managed surgically
*The schematic approach to malignant sexcord/ stromal ovarian tumors is decribed below
*The schematic approach to malignant sexcord/ stromal ovarian tumors is decribed below

Revision as of 16:16, 10 April 2019

Sexcord/ stromal ovarian tumors Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Surgical intervention is not recommended for the management of [disease name].

OR

Surgery is not the first-line treatment option for patients with [disease name]. Surgery is usually reserved for patients with either [indication 1], [indication 2], and [indication 3]

OR

The mainstay of treatment for [disease name] is medical therapy. Surgery is usually reserved for patients with either [indication 1], [indication 2], and/or [indication 3].

OR

The feasibility of surgery depends on the stage of [malignancy] at diagnosis.

OR

Surgery is the mainstay of treatment for [disease or malignancy].

Indications

  • Surgical intervention is not recommended for the management of [disease name].

OR

  • Surgery is not the first-line treatment option for patients with [disease name]. Surgery is usually reserved for patients with either:
    • [Indication 1]
    • [Indication 2]
    • [Indication 3]
  • The mainstay of treatment for [disease name] is medical therapy. Surgery is usually reserved for patients with either:
    • [Indication 1]
    • [Indication 2]
    • [Indication 3]

Surgery

  • Surgery is the mainstay of treatment for sexcord/ stromal ovarian tumors[1][2][3][4][5][6][7][8]
  • Both benign and malignant ovarian sex cord-stromal tumors are managed surgically
  • The schematic approach to malignant sexcord/ stromal ovarian tumors is decribed below
 
 
 
 
 
 
 
 
 
 
 
Malignant sexcord-stromal tumors
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Stage IA/IC: fertility desired
 
 
 
All others
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Fertility sparing surgery with complete staging
 
 
 
Complete staging
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Stage I, low risk
 
Stage I high risk(eg, ruptured stage IC or poorly differentiated stage I) or Intermediate risk(eg, heterologous elements
 
Stage II-IV
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Observe
 
Observe or consider platinum based chemotherapy
 
platinum based chemotherapy or radiotherapy for limited disease
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Surveillance
 
Surveillance
 
Surveillance
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If clinical relapse: Clinical trial, consider secondary cytoreductive surgery, or recurrence therapy

Contraindications

References

  1. Gurumurthy M, Bryant A, Shanbhag S (April 2014). "Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent)". Cochrane Database Syst Rev (4): CD006912. doi:10.1002/14651858.CD006912.pub2. PMID 24753008.
  2. Gremeau AS, Bourdel N, Jardon K, Rabischong B, Mage G, Pouly JL, Canis M (January 2014). "Surgical management of non-epithelial ovarian malignancies: advantages and limitations of laparoscopy". Eur. J. Obstet. Gynecol. Reprod. Biol. 172: 106–10. doi:10.1016/j.ejogrb.2013.10.023. PMID 24315353.
  3. Schultz KA, Schneider DT, Pashankar F, Ross J, Frazier L (May 2012). "Management of ovarian and testicular sex cord-stromal tumors in children and adolescents". J. Pediatr. Hematol. Oncol. 34 Suppl 2: S55–63. doi:10.1097/MPH.0b013e31824e3867. PMID 22525408.
  4. Gershenson DM (June 2012). "Current advances in the management of malignant germ cell and sex cord-stromal tumors of the ovary". Gynecol. Oncol. 125 (3): 515–7. doi:10.1016/j.ygyno.2012.03.019. PMID 22426486.
  5. Färkkilä A, Haltia UM, Tapper J, McConechy MK, Huntsman DG, Heikinheimo M (August 2017). "Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary". Ann. Med. 49 (5): 435–447. doi:10.1080/07853890.2017.1294760. PMID 28276867.
  6. Uma Devi K, Purushotham N, Jayashree N (2015). "Management of Ovarian Cancer In Younger Women". Rev Recent Clin Trials. 10 (4): 263–9. PMID 26411956.
  7. Qian Q, You Y, Yang J, Cao D, Zhu Z, Wu M, Chen J, Lang J, Shen K (April 2015). "Management and prognosis of patients with ovarian sex cord tumor with annular tubules: a retrospective study". BMC Cancer. 15: 270. doi:10.1186/s12885-015-1277-y. PMC 4408581. PMID 25886261.
  8. Chatziioannidou K, Botsikas D, Tille JC, Dubuisson J (May 2015). "Preservation of fertility in non-Peutz-Jegher syndrome-associated ovarian sex cord tumour with annular tubules". BMJ Case Rep. 2015. doi:10.1136/bcr-2014-207841. PMC 4434316. PMID 25969483.

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