Secondary adrenal insufficiency classification
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
OR
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
OR
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
OR
If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
OR
The staging of [malignancy name] is based on the [staging system].
OR
There is no established system for the staging of [malignancy name].
Classification
Adrenal insufficiency is classified into 3 types based on the level of impairment.
- Primary adrenal insufficiency
It is due to impairment of the adrenal gland, 80% due to an autoimmune disease called Addison's disease or autoimmune adrenalitis. One subtype is called idiopathic, meaning of unknown cause. Other cases are due to congenital adrenal hyperplasia or an adenoma (tumor) of the adrenal gland.
- Secondary adrenal insufficiency
It is caused by impairment of the pituitary gland or hypothalamus. The principal causes include pituitary adenoma (which can suppress production of adrenocorticotropic hormone (ACTH) and lead to adrenal deficiency unless the endogenous hormones are replaced); and Sheehan's syndrome, which is associated with impairment of only the pituitary gland.
| Adrenal Insufficiency | |||||||||||||||||||||||||||||||||||||
| Primary adrenal insufficiency | Secondary adrenal insufficiency | ||||||||||||||||||||||||||||||||||||
| •Addison's disease •Autoimmune adrenalitis •Idiopathic | Hypopituitarism •Tumors-Craniopharyngioma •Infections- Tuberculosis[1][2] , Histoplasmosis [3] •Pituitary infarction-Sheehan's syndrome, Pituitary apoplexy •Removal of pituitary due to metastasis •Lymphycytic hypophysitis •Head trauma •Intracranial artery aneurysms Drugs •Chronic high dose steroid •Opiates- Codeine, Morphine Genetic causes •Isolated ACTH deficiency •POMC deficiency •Combined Pituitary Hormone Deficiency (CPHD) | ||||||||||||||||||||||||||||||||||||
References
- ↑ Al-Mamari A, Balkhair A, Gujjar A, Ben Abid F, Al-Farqani A, Al-Hamadani A, Jain R (2009). "A case of disseminated tuberculosis with adrenal insufficiency". Sultan Qaboos Univ Med J. 9 (3): 324–7. PMC 3074785. PMID 21509318.
- ↑ Upadhyay, Jagriti; Sudhindra, Praveen; Abraham, George; Trivedi, Nitin (2014). "Tuberculosis of the Adrenal Gland: A Case Report and Review of the Literature of Infections of the Adrenal Gland". International Journal of Endocrinology. 2014: 1–7. doi:10.1155/2014/876037. ISSN 1687-8337.
- ↑ Bhansali A, Das S, Dutta P, Walia R, Nahar U, Singh SK; et al. (2012). "Adrenal histoplasmosis: unusual presentations". J Assoc Physicians India. 60: 54–8. PMID 23777028.