Scleroderma: Difference between revisions

	Scleroderma Microchapters
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Overview
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Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
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X Ray
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Case #1
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Revision as of 19:42, 2 May 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: M. Khurram Afzal, MD [2] Cafer Zorkun, M.D., Ph.D. [3]

For patient information click here

Synonyms and keywords: Systemic sclerosis; CREST syndrome; limited scleroderma; progressive systemic sclerosis; localized scleroderma; mixed connective disease; morphea - linear; sclerosis, systemic; systemic scleroderma

Click here for The Heart in Scleroderma

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Scleroderma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

Template:Diseases of the musculoskeletal system and connective tissue

de:Sklerodermie it:Sclerodermia he:סקלרודרמה nl:Sclerodermie sk:Sklerodermia sv:Sklerodermi

Template:WikiDoc Sources

@@ Line 1: / Line 1: @@
 __NOTOC__
-{{DiseaseDisorder infobox |
-  Name           = Systemic sclerosis |
-  ICD10          = {{ICD10|M|34||m|30}} |
-  ICD9           = {{ICD9|710.1}} |
-  ICDO           = |
-  Image          = Scleroderma-301.jpg|
-  Caption        = MCP, PIP and DIP joints destructions in patient with Scleroderma. <br> [http://www.radswiki.net Image courtesy of RadsWiki]|
-  OMIM           = 181750 |
-  MedlinePlus    = 000429 |
-  DiseasesDB     = 12845 |
-  MeshID         = D012595 |
-}}
 {{Scleroderma}}
+{{CMG}}; '''Associate Editor-In-Chief:''' {{MKA}} {{CZ}}
-{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}
 '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
-{{SK}} Systemic sclerosis
+{{SK}} Systemic sclerosis; CREST syndrome; limited scleroderma; progressive systemic sclerosis; localized scleroderma; mixed connective disease; morphea - linear; sclerosis, systemic; systemic scleroderma
 ===Click [[The Heart in Progressive Systemic Sclerosis (Scleroderma)|here]] for The Heart in Scleroderma===
-==Overview==
+==[[Scleroderma overview|Overview]]==
-== Epidemiology ==
+==[[Scleroderma historical perspective|Historical Perspective]]==
-==Pathophysiology==
+==[[Scleroderma classification|Classification]]==
-==Etiology==
+==[[Scleroderma pathophysiology|Pathophysiology]]==
-==Types of Scleroderma==
+==[[Scleroderma causes|Causes]]==
-==Diagnosis==
+==[[Differentiating Scleroderma from other diseases|Differentiating Scleroderma from other Diseases]]==
-Diagnosis is by clinical suspicion, presence of autoantibodies (specifically [[anti-centromere antibodies|anti-centromere]] and anti-scl70/[[anti-topoisomerase antibodies]]) and occasionally by biopsy. Of the antibodies, 90% have a detectable [[anti-nuclear antibody]]. Anti-centromere antibody is more common in the limited form (80-90%) than in the systemic form (10%), and anti-scl70 is more common in the diffuse form (30-40%) and in African-American patients (who are more susceptible to the systemic form).<ref name=JimenezDerk>{{cite journal |author=Jimenez SA, Derk CT |title=Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis |journal=Ann. Intern. Med. |volume=140 |issue=1 |pages=37-50 |year=2004 |pmid=14706971 |doi=}}</ref>
+==[[Scleroderma epidemiology and demographics|Epidemiology and Demographics]]==
-In 1980 the American College of Rheumatology agreed upon diagnostic criteria for scleroderma.<ref>{{cite journal |author= |title=Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee |journal=Arthritis Rheum. |volume=23 |issue=5 |pages=581-90 |year:1980 |pmid=7378088 |doi=}} Available online at {{cite web | title=Criteria for the Classification of Systemic Sclerosis 1980| work= | url=http://www.rheumatology.org/publications/classification/systsclr.asp | accessdate:5 August 2007}}</ref>
+==[[Scleroderma risk factors|Risk Factors]]==
-Diffuse scleroderma can cause [[musculoskeletal system|musculoskeletal]], [[lung|pulmonary]], [[gastrointestinal tract|gastrointestinal]], [[kidney|renal]] and other complications.<ref name=Primer/>Patients with larger amounts of cutaneous involvement are more likely to have involvement of the internal tissues and organs.
+==[[Scleroderma screening|Screening]]==
-===[[The heart in progressive systemic sclerosis (scleroderma)|Cardiovascular Symptoms]]===
+==[[Scleroderma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
-===Skin Symptoms===
+==Diagnosis==
+[[Scleroderma diagnostic study of choice|Diagnostic Study of Choice]] | [[Scleroderma history and symptoms|History and Symptoms]] | [[Scleroderma physical examination|Physical Examination]] | [[Scleroderma laboratory findings|Laboratory Findings]] | [[Scleroderma electrocardiogram|Electrocardiogram]] | [[Scleroderma x ray|X Ray]] | [[Scleroderma CT|CT]] | [[Scleroderma MRI|MRI]] | [[Scleroderma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Scleroderma other imaging findings|Other Imaging Findings]] | [[Scleroderma other diagnostic studies|Other Diagnostic Studies]]
-===Musculoskeletal System Related Symptoms===
-===Respiratory System Symptoms===
+==Treatment==
+[[Scleroderma medical therapy|Medical Therapy]] | [[Scleroderma surgery|Surgery]] | [[Scleroderma primary prevention|Primary Prevention]] | [[Scleroderma secondary prevention|Secondary Prevention]] | [[Scleroderma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Scleroderma future or investigational therapies|Future or Investigational Therapies]]
-===Gastrointestinal System Related Symptoms===
-===Renal Symptoms===
-== Therapy ==
-===Experimental treatments===
 ==Case Studies==
 [[Scleroderma case study one|Case #1]]
-==References==
-{{Reflist|2}}
-==External links==
-* [http://goldminer.arrs.org/search.php?query=scleroderma Goldminer: Scleroderma]
-* [http://dermnetnz.org/immune/systemic-sclerosis.html DermnetNZ: Systemic sclerosis]
-* [http://www.jsdn.org/ Juvenile Scleroderma Network]
-* [http://www.juvenile-scleroderma.com/ Juvenile Systemic Sclerosis]
-* [http://www.scleroderma.org/ Scleroderma Foundation]
-* [http://www.sclerodermaontario.ca/ Scleroderma Society of Ontario]
-* [http://www.sclero.org/index.html International Scleroderma Network]
-* [http://www.sclerodermaresearch.org/ The Scleroderma Research Foundation]
-* [http://www.sclerodermasociety.co.uk/ UK Scleroderma Society]
-* [http://scleroderma.jhmi.edu/ Scleroderma Information from Johns Hopkins University]
 {{Diseases of the musculoskeletal system and connective tissue}}
@@ Line 81: / Line 44: @@
 [[Category:Autoimmune diseases]]
 [[Category:Diseases involving the fasciae]]
+[[Category:Rheumatology]]
+[[Category:Up-To-Date]]
+[[Category:Primary care]]
+[[Category:Medicine]]
+[[Category:Dermatology]]
 [[Category:Rheumatology]]