Sarcoidosis differential diagnosis: Difference between revisions
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* [[Lymphocytic interstitial pneumonia]] | * [[Lymphocytic interstitial pneumonia]] | ||
* [[Behçet’s disease]] | * [[Behçet’s disease]] | ||
* [[Rheumatoid nodules]<ref name="wasog">Statement on sarcoidosis: Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 160:736–755, 1999.</ref> | * [[Rheumatoid nodules]]<ref name="wasog">Statement on sarcoidosis: Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 160:736–755, 1999.</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Sarcoidosis has many differentials, which can be classified depending on the organ involved, pathologic findings and laboratory findings.
Differential Diagnosis
Sarcoidosis has been defined as a multisystem granulomatous disorder of unknown cause[1], but granulomatous inflammation alone is not sufficient for the diagnosis of sarcoidosis because alternative etiologies of granulomatous inflammation need to be excluded.
Causes of granulomatous reaction beside sarcoidosis
- Mycobacterium tuberculosis
- Mycoplasma
- Pneumocystis jiroveci
- Brucellosis
- Cat-scratch fever
- Atypical mycobacteria
- Toxoplasmosis
- Berylliosis
- Hard metal
- Zirconium
- Tattoo
- Hypersensitivity pneumonitis
- Medications (e.g., methotrexate)
- ANCA-associated vasculitis
- Necrotizing sarcoid granuloma
- Lymphoma
- Cancer
- Granulomatous lesions of unknown significance
- Crohn’s disease
- Lymphocytic interstitial pneumonia
- Behçet’s disease
- Rheumatoid nodules[1]
- ↑ 1.0 1.1 Statement on sarcoidosis: Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 160:736–755, 1999.