Sandbox vidit2
| Drug | Loading dose | Maintenance dose |
| Acute Setting | ||
| Heart rate control in patients without accessory pathway | ||
| ▸ Esmolol (Class of recommendation I Level of evidence C) | ▸ 500 mcg/kg IV over 1 min | ▸ 60 to 200 mcg/kg/min IV |
| ▸ Propanolol (Class of recommendation I Level of evidence C) | ▸ 0.15 mg/kg IV | ▸ NA |
| ▸ Metoprolol (Class of recommendation I Level of evidence C) | ▸ 2.5 to 5 mg IV bolus over 2 min; up to 3 doses | ▸ NA |
| ▸ Diltiazem (Class of recommendation I Level of evidence B) | ▸ 0.25 mg/kg IV over 2 min | ▸ 5 to 15 mg/h IV |
| ▸ Verapamil (Class of recommendation I Level of evidence B) | ▸ 0.075 to 0.15 mg/kg IV over 2 min | ▸ NA |
| Heart rate control in patients with accessory pathway | ||
| ▸ Amiodarone (Class of recommendation IIa Level of evidence C) | ▸ 150 mg over 10 min | ▸ 0.5 to 1 mg/min IV |
| Heart Rate Control in patients with heart failure and without accessory pathway | ||
| ▸ Amiodarone (Class of recommendation IIa Level of evidence C) | ▸ 150 mg over 10 min | ▸ 0.5 to 1 mg/min IV |
| ▸ Digoxin (Class of recommendation I Level of evidence B) | ▸ 0.25 mg IV each 2 h, up to 1.5 mg | ▸ 0.125 to 0.375 mg daily IV or orally |
| Non-Acute Setting and Chronic Maintenance Therapy | ||
| Heart rate control | ||
| ▸ Metoprolol (Class of recommendation I Level of evidence C) | ▸ Same as maintenance dose | ▸ 25 to 100 mg twice a day, orally |
| ▸ Propanolol (Class of recommendation I Level of evidence C) | ▸ Same as maintenance dose | ▸ 80 to 240 mg daily in divided doses, orally |
| ▸ Verapamil (Class of recommendation I Level of evidence B) | ▸ Same as maintenance dose | ▸ 120 to 360 mg daily in divided doses; slow release available, orally |
| ▸ Diltiazem (Class of recommendation I Level of evidence B) | ▸ Same as maintenance dose | ▸ 120 to 360 mg daily in divided doses; slow release available, orally |
| Heart Rate Control in patients with heart failure and without accessory pathway | ||
| ▸ Digoxin (Class of recommendation I Level of evidence B) | ▸ 0.5 mg by mouth daily | ▸ 0.125 to 0.375 mg daily, orally |
| ▸ Amiodarone (Class of recommendation IIb Level of evidence C) | ▸ 800 mg daily for 1 wk, orally 600 mg daily for 1 wk, orally 400 mg daily for 4 to 6 wk, orally |
▸ 200 mg daily, orally |