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==Cholera | =[[sandbox suveen|Cholera]]= | ||
* [[Cholera]] | |||
===Antibiotics=== | ===Antibiotics=== | ||
* [[Antibiotic]] treatments for one to three days shorten the course of the disease and reduce the severity of the symptoms. | * [[Antibiotic]] treatments for one to three days shorten the course of the disease and reduce the severity of the symptoms. | ||
Revision as of 18:39, 7 August 2015
Cholera
Antibiotics
- Antibiotic treatments for one to three days shorten the course of the disease and reduce the severity of the symptoms.
- People can recover even without them, if sufficient hydration and electrolyte balance is maintained.
- Doxycycline is typically used first line, although some strains of V. cholerae have shown resistance.
- Doxycycline single dose 300 mg or tetracycline 12,5 mg/kg 4 time/day for 3 days
- Other antibiotics proven to be effective include cotrimoxazole, erythromycin, tetracycline, chloramphenicol, and furazolidone.[1]
- Fluoroquinolones, such as norfloxacin, also may be used, but resistance has been reported.[2]
- Young children: erythromycin 12,5 mg/kg 4 time/day for 3 days
- for children below 6 months of age: 10 mg daily for 10 days add zinc
- for children 6 months to 5 years of age: 20mg daily for 10 days add zinc
- In many areas of the world, antibiotic resistance is increasing. Testing for resistance during an outbreak can help determine appropriate future choices. In Bangladesh, for example, most cases are resistant to tetracycline, trimethoprim-sulfamethoxazole, and erythromycin. Rapid diagnostic assay methods are available for the identification of multiple drug-resistant cases.[3] New generation antimicrobials have been discovered which are effective against in in vitro studies.[4]
References
- ↑ "Cholera treatment". Molson Medical Informatics. 2007. Retrieved 2008-01-03.
- ↑ Krishna BV, Patil AB, Chandrasekhar MR (2006). "Fluoroquinolone-resistant Vibrio cholerae isolated during a cholera outbreak in India". Trans. R. Soc. Trop. Med. Hyg. 100 (3): 224–6. doi:10.1016/j.trstmh.2005.07.007. PMID 16246383. Unknown parameter
|month=ignored (help) - ↑ Mackay IM (editor) (2007). Real-Time PCR in microbiology: From diagnosis to characterization. Caister Academic Press. ISBN 978-1-904455-18-9.
- ↑ Ramamurthy T (2008). "Antibiotic resistance in Vibrio cholerae". Vibrio cholerae: Genomics and molecular biology. Caister Academic Press. ISBN 978-1-904455-33-2.