Sandbox leucocytosis
- Leukocytosis is defined as an elevated white blood cell (WBC) count greater than 11,000 per mm3 (11.0 × 109 per L).
- The most common type of leukocytosis is neutrophilia.
- Neutrophilia can be defined as an increase in the absolute number of mature neutrophils to greater than 7,000 per mm3 [7.0 × 109 per L].
| Differentiating Symptoms | Differentiating physical exam findings | Differentiating Labs | |||
|---|---|---|---|---|---|
| Physiological variation | Birth | ||||
| Adult | |||||
| Pregnancy | |||||
| Primary | Congenital | Heridatary neutrophilia | |||
| Chronic idiopathic neutrophilia | |||||
| Down syndrome | |||||
| LAD | |||||
| Acquired | CML | ||||
| Polycythemia Vera | |||||
| Secondary | Infection | Acute | |||
| Chronic | |||||
| Connective tissue disorders | RA | ||||
| JRA | |||||
| IBD | |||||
| Chronic hepatitis | |||||
| Drug induced | Steriod | ||||
| Lithium | |||||
| Beta agonists | |||||
| Cytokines | |||||
| Marrow stimulation | Hemolytic anemia | ||||
| Immature thrombocytopenia | |||||
| Post splenectomy | |||||
| Metabolic | Diabetic coma | ||||
| Acidosis | |||||
| Thyroid strom | |||||
| Acute Gout | |||||
| Seizures | |||||